1. Aggregation kinetics of Aβ42 using a protocol with 0
Aggregation kinetics of Aβ42 using a protocol with 0.35 M guanidine hydrochloride.
Aggregation kinetics of Aβ42 using a protocol with 0.35 M guanidine hydrochloride. (a) Kinetics curves in the presence of different ThT concentrations. Aggregation was performed at 37°C without agitation. Protein concentration is 10 µM. The buffer is PBS containing 0.35 M guanidine hydrochloride. (b) Fluorescence at aggregation plateau as a function of ThT concentrations. Symbols represent the average and error bars represent the standard deviation of three experiments. (c) Normalized aggregation curves. (d) Lag time (tlag) and half time (t50) from the aggregation kinetics. Symbols represent average and error bars represent standard deviation of three experiments.
Christine Xue et al. R. Soc. open sci. 2017;4:160696
© 2017 The Authors.