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Practical NO -8- Dalia kamal eldien
Leukemia Practical NO -8- Dalia kamal eldien
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Normal Mature Leukocytes
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Size of the cell: m Shape of the cell: oval or round Colour of cytoplasm: pink Granularity: a few azurophilic and neutrophilic, different in number granulation Nucleus' shape: lobulated (normally less than 5 lobes) Type of chromatin: condensed Nuclear/cytoplasmic ratio: low or very low Nucleoli: not visible Occurrence: blood: % marrow: % Magnification: x 1000
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Size of the cell: 15 - 25 m Shape of the cell: oval or round
Size of the cell: m Shape of the cell: oval or round Colour of cytoplasm: pale, covered by granules Granularity: abundant eosinophilic (orange-red) Nucleus' shape: lobulated, semicircular Type of chromatin: condensed Nuclear/cytoplasmic ratio: low or very low Nucleoli: not visible Occurrence: blood: % marrow: < 2 %
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Shape of the cell: round or oval
Size of the cell: m Shape of the cell: round or oval Colour of cytoplasm: light-pink, mostly covered by granules and nucleus Granularity: very dark, basophilic, granules of various size. The amount varies Nucleus' shape: oval shaped in not mature forms; lobular shaped in mature forms Type of chromatin: condensed, pale Nuclear/cytoplasmic ratio: low or very low Nucleoli: not visible
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Size of the cell: m Shape of the cell: round, oval or irregular Colour of cytoplasm: grey-blue Granularity: absent or a few, azurophilic, very fine granules Nucleus' shape: usually irregular Type of chromatin: coarse chromatin, clumped Nuclear/cytoplasmic ratio: moderate or low Nucleoli: not visible Occurrence: blood: % marrow: < 2 %
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Netrophilia
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Physiological At birth Physical exercise. Emotion Pregnancy.
Following partum.
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Pathological Infection
Pyrogenic: staphylococci, streptococci, pneumococci, and gonococci. Non pyrogenic: rheumatic fever, scarlet fever, diphtheria and poliomyelitis. Septicemia. Haemorrhage trauma: surgical, fracture, crush and burns Malignant disease. carcinoma and sarcoma Cardiac disorders
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Drugs and chemical poisoning.
Metabolic disturbances. renal failure, diabetic coma , gout . Myeloid leukemia. Collagen disease. rheumatoid arthritis, SLE Miscellaneous Serum sickness accompanying intravascular haemolysis.
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Myloblast
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Promylocyte
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LYMPHOBLASTS
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Monoblast
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AML
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ALL
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CML
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CLL
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This is the last practical in hematology, I wish all of you luck and success
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Thank you
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