1. NORE1A mRNA level (NORE1A/GAPDH) NORE1B mRNA level (NORE1B/GAPDH)
1.8
1.6
1.4
1.2
1.0
0.8
0.6
0.4
0.2
I II III
(N=26) (N=18) (N=36)
NORE1A mRNA level (NORE1A/GAPDH)
P < 0.05
WD MD PD
(N=25) (N=46) (N=9)
I II III
NORE1B mRNA level (NORE1B/GAPDH)
WD MD PD B
Percentage of specimens (%) 80 70 60 50 40 30 20 10
NORE1A level
Wild type K-Ras
Mutant K-Ras
Normal Low
(N=49) (N=31) 19 11
NORE1B level 34
(N=55) (N=25) 21 16 9