1. IBS-D -- From Diagnosis to Management

3. Snapshot of IBS-D

4. The Diagnostic Challenges of IBS-D

5. Rome IV Diagnostic Criteria for IBS

6. Rome IV Diagnostic Testing Recommendations

7. Practical Approach to the Workup

8. Key Components of the Patient History

9. Diagnostic Approach

10. Emerging Biomarkers

11. IBS-D Treatment Options

12. Low-FODMAP Diet vs Australian Diet

13. A Low FODMAP Diet vs Modified NICE Guidelines in US Adults With IBS-D

14. Gluten-Free Diet

15. Probiotics Putative Mechanisms of Action

16. Pharmacologic Therapies

17. Loperamide in IBS-D

18. Antispasmodics

19. Global Relief of IBS Symptoms With TCAs or SSRIs

20. Bile Acid Sequestrants

21. Eluxadoline for IBS-D

22. Safety of Eluxadoline in Patients With IBS-D

23. Rifaximin

24. Repeat Treatment With Rifaximin TARGET 3

25. Alosetron for IBS-D

26. Case 5-Year History of Symptoms

27. Abbreviations

28. Abbreviations (cont)