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You will be able to List and define the characteristics of muscle tissue List and explain the functions of muscle tissue List and describe the 3 types of muscle tissue Describe and label the types of deep fascia Describe the microscopic appearance of skeletal muscle Label a typical skeletal muscle fiber Label and describe the regions of a sarcomere
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The scientific study of muscles
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Branch of medicine concerned with the prevention or correction of disorders of the musculoskeletal system
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Excitability – the ability to respond to a stimulus
Contractility – the ability to shorten when stimulated Extensibility – the ability to be stretched Elasticity – the ability to return to the original size
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Motion – body movements as well as moving substances within the body
Posture – postural muscles continuously contract when awake to hold the body upright Heat Production – muscular contraction produces 85% of the body’s heat
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Location – attached to bones
Appearance – striated Nervous Control - Voluntary
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Location – The Heart Appearance – striated Nervous Control - involuntary
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Location – walls of hollow organs
Appearance – non-striated Nervous Control - involuntary
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Fascia – sheets or bundles of fibrous connective tissue
Superficial Fascia – just beneath the skin Deep Fascia – Holds muscles together Epimysium – covers the entire muscle Perimysium – covers a bundle of muscle fibers Endomysium – covers individual muscle fibers
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Tendon – cord-like extension of deep fascia that connects muscle to bone
Aponeurosis – a sheet of connective tissue, similar to a tendon that attaches muscles
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Highly vascular and highly innervated
Need to respond to stimuli (nerves) Uses lots of energy (ATP) so needs blood
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Myofibers – muscle fiber (cell)
Sarcolemma – plasma membrane Sarcoplasm – cytoplasm Sarcoplasmic Reticulum – ER Transverse Tubules (T-Tubules) – tubes that extend across the myofiber and open to the outside.
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Myofibril – structures that make up the fibers
Myofilaments – structures that make up the fibrils Sarcomeres – basic functional unit of skeletal muscles
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http://www. brookscole
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Z-line – end of a sarcomere
A-band – dark area made of thick and thin filaments I-band – light area made of only thin filaments H-zone – light area made of only thick filaments
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Actin – protein that makes the thin filaments
Myosin – protein that makes the thick filaments
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http://highered. mcgraw-hill
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http://highered. mcgraw-hill
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You will be able to Define the sliding filament theory.
Describe the actions of a muscle fiber when it contracts. Label a diagram of a neuromuscular junction. Describe the biochemical steps of a muscle contraction. Discuss where the energy for muscle contraction comes from. Describe the different types of muscle contractions. Label a myogram of a twitch.
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The thin filaments (actin) slide over the thick causing the sarcomere to shorten. This process requires ATP
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Where a muscle is innervated (place where a nerve meets a muscle)
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Nerve Cell
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The nerve that stimulates a muscle to contract
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Axon of a motor neuron that attaches to the sarcolemma of the muscle fiber
← Motor End Plate Muscle → ← Neuron
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The neurotransmitter (chemical) released by a motor neuron that stimulates a muscle to contract
Immunostaining of rat neuromuscular junctions Neurofilament immunofluorescence stain(green) Actylcholine receptor (red)
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The combination of the motor neuron and the muscle it innervates
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An action potential causes the release of Ca+2 ions stimulating the myosin to move the actin filament les/muscles.html (labeling picture)
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Narrated Summary with tabs
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The body uses ATP for energy
This ATP can be produced by the body in 3 ways
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ADP + P + Energy → ATP Fast Not a lot of energy
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1C6H12O6 → 2C3H6O3 + ATP Glucose is broken down into Pyruvic Acid
Needs no oxygen Not a lot of ATP
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1C3H6O3 + O2 → CO2 + H2O + ATP Starts with Pyruvic Acid from Anaerobic
Needs Oxygen to take place Makes a lot of energy Many Steps - longest
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The muscle cells burn off the ATP they have floating around in about 3 seconds.
The phosphagen system kicks in and supplies energy for 8 to 10 seconds. This would be the major energy system used by the muscles of a 100-meter sprinter or weight lifter, where rapid acceleration, short-duration exercise occurs. If exercise continues longer, then the glycogen-lactic acid system (anaerobic) kicks in. This would be true for short-distance exercises such as a 200- or 400-meter dash or 100-meter swim. Finally, if exercise continues, then aerobic respiration takes over. This would occur in endurance events such as an 800-meter dash, marathon run, rowing, cross-country skiing and distance skating.
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When a muscle fiber is stimulated it either completely contracts or does not contract at all
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Threshold Stimulus – the weakest stimulus that can cause a muscle to contract
Sub-Threshold Stimulus – a stimulus that is too weak to cause a contraction
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A record of the electrical activity of a muscle to determine the type of contraction
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A rapid, jerky response to a single stimulus
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Latent Period – time between the application of the stimulus and the muscle contraction
Contraction Period – time when filament are sliding over each other, causing a contraction Relaxation Period – Time during which filaments are sliding back into place Refractory Period – Time following a contraction during which a muscle is unable to respond to a stimulus
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Contraction Period Relaxation Period Latent Period Refractory Period
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A sustained contraction
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A muscle contracts more forcefully after contracting several times
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Tension remains constant but the muscle shortens
Lifting something
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Tension increases but muscle does not shorten
Pulling up on chair
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Wasting away of muscle
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Increase in the size of muscle fibers
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