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Interneurons Scratch an Itch

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Presentation on theme: "Interneurons Scratch an Itch"— Presentation transcript:

1 Interneurons Scratch an Itch
Paula Juliana Seadi Pereira, Ethan A. Lerner  Neuron  Volume 82, Issue 3, Pages (May 2014) DOI: /j.neuron Copyright © 2014 Elsevier Inc. Terms and Conditions

2 Figure 1 Interneurons that Release Dynorphin Modulate Itch
Neurons that respond to itch, cold, and noxious stimuli innervate and are modulated by B5-I interneurons that produce dynorphin. Capsaicin, mustard oil, and menthol activate TRPV1, TRPA1, and TRPM8, respectively. B5-I, inhibitory neurons that are a focus of the report to which this Preview is directed. GRPR, gastrin-releasing peptide receptor. Npra, natriuretic peptide receptor A is the receptor for the B-type natriuretic peptide BNP, also known as Nppb. Image modified and reproduced under CC-BY license: Neuron  , DOI: ( /j.neuron ) Copyright © 2014 Elsevier Inc. Terms and Conditions

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