1. Exploring Membrane Structure and Function Research-Based, Interdisciplinary STEM Education (RISE)

2. Today’s Agenda: Introduction to the Cell Membrane
Intermolecular Forces and Membrane Transport
For Next Week:
Read the papers provided and prepare a brief summary with two+ questions

3. The Fluid Mosaic Model of the Cell Membrane

4. Key Structural Component: The Phospholipid
Think/ Pair/ Share: What do you notice about the structure of this molecule?
Think/ Pair/ Share: What does this mean for the intermolecular forces between these molecules?

5. London Dispersion Forces

6. Dipole-Dipole Forces

7. Hydrogen Bonds Figure: 10-06-02UN Title: Hydrogen bonding Caption:
Hydrogen bonds are also found between molecules of water and molecules of ammonia. They are defined as the attractive interaction between a hydrogen atom bonded to a very electronegative atom (O, N, or F) and an unshared electron pair on another electronegative atom.

8. Key Structural Component: The Phospholipid

9. Key Structural Component: A Mosaic of Proteins

10. A Quick Look at Protein Structure

11. A Quick Look at Protein Structure

12. Key Features of Membrane Proteins
Think/ Pair/ Share: What must be true about the structure of proteins that span the cell membrane?

13. Visualizing the Cell Membrane:

14. Crossing the Cell Membrane
What types of things does a cell need to get across its membrane?
Of those things, which can cross freely?? Why?? What about everything else??

15. X Cell membranes are SELECTIVELY PERMEABLE
O2, CO2, and other small, nonpolar molecules; and H2O
large, polar molecules; ions
such as H+, Na+, CI-, Ca++; X

16. Your Challenge:
Use your understanding of protein structure to construct a model (drawing) of what a water channel in a cell membrane would look like, and how it would orient itself in a plasma membrane.
Would such a channel need to be specific for water? If so, how could it accomplish this specificity?

17. For Next Week:
Read the papers provided and prepare a brief summary with two+ questions