1. Science Starter
Silently take a seat and think about the following questions (you do not need to write anything down, just think!)
Think about a time when you wanted to standup for something, speak out, or act but you didn’t (can be small or big)
How do you think things might have been different had you acted/spoke?

2. Today’s Agenda Science Starter Ted Talk: Danger of Silence
Unit 1 Test, Grades, & Data Tracker
Unit 2: Cells & Tissues
Into to Cell Structure & Organelles

3. Unit 1 Test & Grades
Unit 1 Test is out of 40 points, score is in the top right
Progress report includes test, score is out of 100
Your progress report does not have letter grades
Class average on test was 86.5!! (Big Goal #1)
Your assignments will also be returned today, put them in your binder
**When I check for completion, usually just out of: A:
B: 80-89
C: 70-79
D: 60-69
F: 0-59
= 50%
+ = 100 %
= 85 %
- = 70 %

4. Data Tracker
Enter in how many question you had correct for each objective
Divide the amount you had correct by the total number of questions in the objective, this is your percentage!
The goal is to be 85% or above in each category
The tracker should be completed, stapled to the front of your test with name on it and placed in the bin
If you do not return test you will have a zero in the gradebook!

5. Unit 2: Cells & Tissue 2.1a- Cell Structure & Organelles
2.1b- Cell Membrane Transport
2.2a- Location & Function of Tissue
2.2b- Identify Tissue Types

6. Into the Cell…

7. Understand the Structure of Cells and the Function of Organelles
Objective 2.1a
Understand the Structure of Cells and the Function of Organelles

8. Cells
Anatomy & Physiology

9. What do you think situs inversus is?
Mackenzie, at 4 years old, was diagnosed with pneumonia. Her parents were worried, it seemed that Mackenzie was always sick. She always had a runny nose and had frequent ear infections. The diagnosis of pneumonia also revealed something else - Mackenzie had a condition known as situs inversus.
What do you think situs inversus is?
2. How might Mackenzie’s condition be related to cell dysfunction?
This mini case is based on a real person (Source), images are stock images from morguefile.com

10. Cells vary in SIZE and STRUCTURE
Depends on what they do

11. Cell Membrane is selectively permeable
Cytology = the study of cells
All Animal Cells have 3 main parts
Nucleus
Cytoplasm (cytosol)
Cell Membrane
Cell Membrane is selectively permeable

12. Lipid bilayer (phospholipids) make up the membrane with proteins embedded to help regulate what comes across the membrane

13. Given Mackenzie’s history of illness, sniffles, and ear infections, doctors wanted to rule out cystic fibrosis. A simple “sweat test” is used to diagnose CF.
Examine the image. Why is CF considered a disorder related to the cell membrane.
Could CF have caused Mackenzie’s symptoms?
The sweat test showed that Mackenzie did not have extra chloride in her sweat. Does this mean that she does not have CF? Could there be another cause for Mackenzie’s frequent infections?

14. ORGANELLES-  "little organs" within the cell that perform specific functions

16. Doctors wanted to test Mackenzie for a disorder called “PRIMARY CILIARY DYSKINESIA”
This disorder causes cells to not create normal cilia.
Cells scraped from the sinuses showed an irregularity in Mackenzie’s cilia.
What is different about this cilia?
Why would problems with cilia cause pneumonia, ear infections, and a constant runny nose?

17. What about the situs inversus?
Mackenzie can live with PCD, but she will always have a cough and deal with lung and ear infections.
What about the situs inversus?
Doctors have warned her parents that when she gets older, she may have trouble conceiving a child and is at risk for an ECTOPIC pregnancy.
What role does cilia play in reproduction?
It is believed that the motion of cilia may play a part in determining the placement of organs within the thoracic and abdominal cavities. In the absence of ciliary motion, organ placement becomes a random event, giving each affected embryo a 50/50 chance of having typical or atypical placement.

19. Exit Quiz Complete Exit Quiz using what you know about cell organelles
This will help us know what we need to review tomorrow!
Try your best and do not use notes/people around you!
Turn into the blue bin before you leave today

20. The cytoplasm (cytosol) is the area between the nucleus and the membrane.
Many of the cell’s metabolic reactions occur in this area.
Do you remember what metabolism is?

21. ENDOPLASMIC RETICULUM
Transport system; canals and channels that connect membrane to nucleus and to organelles within the cell
Smooth ER (lipid synthesis)
Rough ER (contains ribosomes for protein manufacture)

22. Golgi Apparatus
Flattened membranes; package and delivery of proteins produced by the ribosomes
Proteins are exported in vesicles

23. Mitochondria ( The “powerhouse” of the cell )
Chemical energy from food is converted to a useable form (ATP) process is called Cellular Respiration
What does respiration have to do with metabolism?

24. Lysosomes - contain digestive enzymes to break down substances (“suicide sac”)
Enzymes break down substances in the cell, such as food or worn out cell parts, even bacteria.
Remember the video on how beans become farts?
What is the enzyme in this image and how do you know?
What organ is your body is most like the lysosome?

25. Centrosome – two cylinders, centrioles, that sit perpendicular
During cell division, the centrioles separate and form a spindle.
The spindle moves chromosomes during cell division so that each new cell gets the proper number.

26. CYTOSKELETON
made of microfilaments and microtubules which maintain shape and functions in movement
Cilia & Flagella

27. NUCLEUS - (the “brain” of the cell)
Directs cell activities (the “brain” of the cell)
Contains genetic information (DNA) in the form of chromatin
Also contains a nucleolus – makes ribosomes
Has tiny pores in the nuclear membrane is where RNA can exit the nucleus