1. History of Vaccines
Variolation: inoculation of smallpox into skin (eighteenth century)
Vaccination:
Inoculation of cowpox virus into skin (Jenner)
Inoculation with rabies virus (Pasteur)

2. Chapter 18, unnumbered figure B, page 510, Reported numbers of measles cases in the United States, 1960–2010. (CDC, 2010)
140
120
Vaccine
licensed
100
500,000 80
Reported number of cases
450,000 60 40
400,000 20
350,000
300,000
2000 01 02 03 04 05 06 07 08 09 10
Reported number of cases
Year
250,000
200,000
150,000
100,000
50,000
1960
1965
1970
1975
1980
1985
1990
1995
2000
2005
2010
Year

3. Vaccines Used to Prevent Bacterial Diseases
Diphtheria
Purified diphtheria toxoid
Meningococcal meningitis
Purified polysaccharide from Neisseria meningitidis
Pertussis (whooping cough)
Inactivated toxin plus acellular fragments of Bordetella pertussis
Pneumococcal pneumonia
Purified polysaccharide from seven strains of Streptococcus pneumoniae
Tetanus
Purified tetanus toxoid
Haemophilus influenzae type b meningitis
Polysaccharide from Haemophilus influenzae type b conjugated with protein to enhance effectiveness

4. Vaccines Used to Prevent Viral Diseases
Influenza
Injected vaccine, inactivated virus (nasally administered: attenuated virus)
Measles
Attenuated virus
Mumps
Rubella
Chickenpox
Poliomyelitis
Killed virus

5. Vaccines Used to Prevent Viral Diseases
Rabies
Killed virus
Hepatitis B
Antigenic fragments of virus
Hepatitis A
Inactivated virus
Smallpox
Live vaccinia virus
Herpes zoster
Attenuated virus
Human papillomavirus

6. Vaccines for Persons Aged 0–6 Years
Hepatitis B
Rotavirus
DTaP
Haemophilus influenzae type b
Pneumococcal
Inactivated poliovirus
Influenza

7. Vaccines for Persons Aged 0–6 Years
MMR*
Varicella*
Hepatitis A
Meningococcal
* As of 2012 it is not MMRV

8. Types of Vaccines Attenuated whole-agent vaccines
MMR vaccine
Inactivated whole-agent vaccines
Salk polio vaccine
Toxoids
Tetanus vaccine

9. Types of Vaccines Subunit vaccines Nucleic acid (DNA) vaccines
Acellular pertussis
Recombinant hepatitis B
Nucleic acid (DNA) vaccines
West Nile (for horses)