1. Experience with clearing herds for BVDV infections Practitioner Jørgen Katholm Vivild Denmark

4. Herds with PI 1988-1994

5. Herds with PI 1988-1994

8. Herds with PI 1988-1994

13. Herds with PI 1988-1994

16. Herds with PI 1988-1994

18. Herds with PI 1988-1994

20. Herds with PI 1988-1994 (2 beef herds)

21. Herd symptoms months from birth of PI calv -9 - -6Recycling -9 - -6 Diarrea, cows, reduced milk Dead cows -6 - -4reduced immunity, severe coliform mastitis, ringworm, pyogenes infections. High Bulk milk cell count -6 - -1Abortion storm -6 - -2week calves born, calf diarrea, (Seropositive calves) -7 - 0Growth retarded calves -1 - 0malformated calves, blind -1 - 0Stillbirth 0 - 2PI calves -1 - 2Retaind placenta 0 - 3Week calves, diarrea 1 - 4Lunginfections 2 - ?Sudden death of PI calves Mucosal Disease

22. BVD Eradication Individual marking:Ear tags (database) Trade restrictionsBiosecurity (status of BVD) Blood testingRelaibel tests PRICE Education of vets.Brownlie, Alenius, Kalis Practising Vets Education of farmersVets from farmer organisations Local vets Trend setting FarmersFree of infection Infected - Time scale of disease

23. All Herds infected and clean 1994 Trend setters Free 5-10 years

24. First eradication 1990-91

25. BVD Eradication plan 1990Test all cattle for antibodies (PRICE – Holland 1/3) Test all negative for virus by virusculture Herd status antibody in 5 bloodsamples 1994 Test all cattle > 3 month for virus (ELISA) Until 1 year after last PI no antibod testing (PRICE) Farmers organisation started volontary BVD-Status Milk: 4 times/yearBeef 3 blood for antibodies/year Infection stops to spread BUT 3 farms bought seropositive heifers calving with PI

26. All Herds infected and clean 1994

27. Beef Herds Infected 1996

28. Beef Herds in Vivild Total infected 10herds 8 with PI

29. Beef Herds Infected 1999

30. Last PI Beef herd killed 8 dec 1999

31. Milking Herds infected and clean 1994

32. Milking Herds Infected 1995

33. Milking Herds in Vivild total 54 infected 40 with PI

34. Milking Herds Infected 1999

35. Milking Herds Infected 2000

37. Last PI killed 16 jan 2001

38. All Herds 2003 Free

39. Normal calves negative 8 month 1 HF calv positive 10 months negativ 14 months 1 beef calv positive12 months negativ 13 months Maternel antibodies

41. BVD antibodies in Charolais young stock 939 930 938 925 937 931 920 915 934 919 929 916 911 926 921 923 912 933 935 922 913 924 936 917 910 927 918 27832-892 940 928 914

42. BVD antibodies in Charolais young stock 22/12 1998 7 calves dehorned + 1 BVD antibodies 939 930 938 925 937 931 920 915 934 919 929 916 911 926 921 923 912 933 935 922 913 924 936 917 negativ 910 927 918 27832-892 940 928 914

43. BVD antibodies in Charolais young stock 5/3 1999 3 BVD blodsamples for status 939 930 938 925 937 931 920 915 934 919 929 916 911 926 921 923 positive 912 933 positive 935 922 positive 913 924 936 917 910 927 918 27832-892 940 928 914

44. BVD antibodies in Charolais young stock 18/3 1999 5 BVD blodsamples 939 930 938 925 937 931 920 915 934 919 929 916 911 926 921 923 positive 912 933 positive 935 922 positive 913 924 936 917 positiv 910 927 918 27832-892 negative 940 928 914

45. BVD antibodies in Charolais young stock 27/4 1999 BVD blodsamples all herd 939 negative 930 negative 938 negative 925 negative 937 negative 931 negative 920 negative 915 negative 934 negative 919 negative 929 negative 916 negative 911 negative 926 negative 921 negative 923 positive 912 negative 933 positive 935 negative 922 positive 913 negative 924 negative 936 negative 917 positiv 910 negative 927 negative 918 positiv 27832-892 negative 940 negative 928 negative 914 negative

46. Conclusions Happy farmers will spread the news Biosecurity - stops the infection Eradication - straight forwad When going for the virus and the tests are reliable Big herds maybe prolonged eradication seperated flocks selling of young calves No spread from Bull stations by semen Injections with infected medicine can cause acute infection

49. Thank you For BVD eradication