1. TCI 1 g/ml3 g/ml5 g/ml7 g/ml9 g/ml11 g/ml CRI loading dose mg/kg 0.31.01.52.0 CRI μg/kg/min2369115161207253 MAC base 2.2 +/- 0.2% 2.14 %1.88 %1.66 %1.47 %1.33 %1.06 % Lidocaine TCI - CRI Comparison Assessment of the hemodynamic effects of lidocaine administered IV in isoflurane-anesthetized cats. Pypendop BH, Ilkiw JE. Am J Vet Res. 2005 Apr;66(4):661-8. This represents high end loading with 1.4x high end CRI dose rate The point at which statistically significant adverse effects were noted

2. 161 g/kg/min 10-50 g/kg/min Assessment of the hemodynamic effects of lidocaine administered IV in isoflurane-anesthetized cats. Pypendop BH, Ilkiw JE. Am J Vet Res. 2005 Apr;66(4):661-8.

3. 10-50 g/kg/min 161 g/kg/min Assessment of the hemodynamic effects of lidocaine administered IV in isoflurane-anesthetized cats. Pypendop BH, Ilkiw JE. Am J Vet Res. 2005 Apr;66(4):661-8.

4. 10-50 g/kg/min 161 g/kg/min Assessment of the hemodynamic effects of lidocaine administered IV in isoflurane-anesthetized cats. Pypendop BH, Ilkiw JE. Am J Vet Res. 2005 Apr;66(4):661-8.

5. (69 g/kg/min) (115 g/kg/min) Assessment of the hemodynamic effects of lidocaine administered IV in isoflurane-anesthetized cats. Pypendop BH, Ilkiw JE. Am J Vet Res. 2005 Apr;66(4):661-8.