1. Catalyst What did you enjoy most about winter break?
By the end of the day today, SWBAT…
Identify the monomer and polymer of DNA
Describe components of a nucleotide
What did you enjoy most about winter break?
Tuesday, January 9, 2017

2. By the end of the day today, SWBAT…
Identify the monomer and polymer of DNA
Describe components of a nucleotide
Why it matters in LIFE:
DNA is what makes you WHO YOU ARE. It is what makes each and every human being (and organism) on Earth unique!

3. Agenda Catalyst 5 min Expectations Review 10 min
Goal Setting/ What Do You Know
Guided Notes on DNA
20 min
Closing

4. Set some goals!
Unit 3: DNA

5. DNA is a macromolecule?
A macromolecule is a very large molecule made of many smaller units

6. “Mono” means….
Monogamy
Monotonous

7. ONE
MONO means

8. “Poly” means….
Polytheism
Polygons
Polygamy

9. MANY
POLY means

10. Monomers and Polymers
Monomers are the repetitive units of a polymer
Polymers are long molecules built from repeating monomers

11. What is the monomer?

12. What is the monomer?
ABCABCABCABCABCABC

13. In your packet….
Train Car
Chain
Pearl

14. DNA
DNA stands for Deoxyribonucleic Acid

15. Function of DNA
DNA contains genetic information and controls the production of proteins in a cell
Proteins are the building blocks of an organism

16. Where is DNA found?
DNA is found in the nucleus of every single cell in our bodies

17. Structure of DNA DNA is a type of nucleic acid
The monomer of DNA is a nucleotide

18. Nucleotide Structure 2. A Phosphate Group 3. A Nitrogen Base
1. A Sugar (Deoxyribose)

19. Bases: Purines and Pyrimidines
Adenine and Guinine are Purines
Thymine and cytosine are Pyrimidines

20. Base Pairing Rules
A with T C with G

21. Sequence
It is the sequence, or order, of nitrogen bases that determines which proteins are made

22. DNA structure
The DNA double helix is 2 strands of DNA held together by hydrogen bonds

23. Chromosomes
The DNA double helix associates with proteins to form chromosomes

24. Practice In Your Packet

25. What it’ll look like on the test…

26. Catalyst What are the three components of a nucleotide?
By the end of the day today, SWBAT…
Model the structure of DNA
What are the three components of a nucleotide?
Wednesday, January 11, 2016

27. By the end of the day today, SWBAT…
Model the structure of DNA
Why it matters in LIFE:
DNA is what makes us all unique. It’s STRUCTURE is what allows it to do it’s job!

28. What it’ll look like on the test…
If a sample of DNA contains 33% Cytosine, how much Guanine does it contain?

29. Agenda Catalyst 5 min Expectations DNA Modeling Mini-Lab 30 min
Closing

30. What type of macromolecule is DNA?
Nucleic Acid

31. What are the building blocks of DNA?
Nucleotides

32. What are the three parts of a nucleotide?
Sugar, Phosphate, Nitrogen Base

33. What are the two types of nitrogen bases?
Purines and Pyrimidines

34. What is the backbone of DNA made of?
Sugar and Phosphate

35. What type of bond holds together the two strands of DNA?
Hydrogen Bonds

36. Adenine bonds to what other base?
Thymine

37. Guanine bonds to what other base?
Cytosine

38. Guanine bonds to what other base?
Cytosine

39. What is the shape of DNA called?
Double Helix

40. Write the complimentary base pairing:
ATTCAGCCT
TAAGTCGGA

41. Label the DNA picture Include the following: Sugar Phosphate Adenine
Thymine
Cytosine
Guanine
Hydrogen bonds
Nucleotide

42. Create a model of DNA using your materials
Make sure you include a key at the bottom!

43. What it’ll look like on the test…
If a sample of DNA contains 33% Cytosine, how much Guanine does it contain?

44. Catalyst What are the two purines? By the end of the day today, SWBAT…
Summarize the steps of DNA replication
Thursday, January 12, 2017

45. By the end of the day today, SWBAT…
Summarize the steps of DNA replication
Why it matters in LIFE:
This process allows our cells to divide, which happens CONSTANTLY. If replication doesn’t happen correctly, we end up with mutations

46. What it’ll look like on the test…

47. Agenda Catalyst 5 min DNA Replication Guided Notes 15 min
Modeling Replication
10 min
Cahoot
Closing/Ticket Drawing

49. DNA Replication
During DNA replication, DNA makes a copy of itself to prepare for cell division

50. Unzipping the DNA Double Helix
An enzyme called helicase breaks apart the hydrogen bonds that connect the two strands of DNA, like a zipper

51. Template strands
These strands of DNA are called template strands, because they are the template for making the other side of the DNA

52. Base-Pairing
As the old DNA unzips, free nucleotides (which are waiting in the nucleus) come and attach themselves according to base- pairing rules (A with T , C with G )

53. DNA Polymerase
An enzyme called DNA Polymerase joins the nucleotides together to produce a new DNA molecule

54. DNA Polymerase
DNA Polymerase also proofreads the new DNA molecules for errors

55. By the End…
After replication is complete, there are 2 new double helicies

56. Semi-Conservative
DNA replication is called semi- conservative, because half of the new DNA molecule is old, and half is new

57. In a nutshell: Helicase unzips DNA
DNA polymerase brings in new nucleotides
End up with 2 identical DNA molecules

58. Modeling DNA Replication
“Unzip” your strand of DNA using Helicase
Glue down both template strands
Complete the new DNA strands using base-pairing rules

59. Replication Re-cap… What did the scissors represent?
What do the green strands of DNA represent?
As you generated new nucleotides, what enzyme were you acting like?

60. Cahoot!
Keep track of your CORRECT responses
5 tickets to winner
Notes for the first 6 ONLY!

61. The purpose of DNA replication is to prepare for ______ ___________
Cell Division

62. What is the name of the enzyme that unzips DNA?
Helicase

63. The two original strands of DNA are called the ___________ strands
template

64. What is the name of the enzyme that proofreads replication for errors?
DNA Polymerase

65. After replication is complete, there are ____ identical double helices2

66. NO
MORE
NOTES! 
After replication, half of the DNA is old, half is new. Therefore, we call it…
Semi-Conservative

67. Write the complimentary strand for the base sequence ATCCGAC
TAGGCTG

68. What type of macromolecule is DNA?
Nucleic Acid

69. What are the building blocks of DNA?
Nucleotides

70. What are the three parts of a nucleotide?
Sugar, Phosphate, Nitrogen Base

71. Adenine pairs with…
Thymine

72. What is the backbone of DNA made of?
Sugar and Phosphate

73. What type of bond holds together the two strands of DNA?
Hydrogen Bonds

74. Guanine pairs with…
Cytosine

75. What is the shape of DNA called?
Double Helix

76. So let’s take another look at this…