1. Experimental Design Jan 9, 2004
Stats 11, Winter 2004
Experimental Design
Jan 9, 2004

2. London Cholera Outbreak, 1854
Cholera kills quickly
Primary symptom is severe diarrhea
• Modern treatment involves an IV to provide hydration
• Competing Theories for transmission: air vs water (germs). Air was the predominant view.

3. Golden Square, Sept 1854 Unusually intense, deadly outbreak
500 deaths in just a few days
Local panic made neighbors flee
John Snow, a physician, believed cholera spread through polluted water supplies

6. Is this definitive "proof"?

7. Same picture, but with daily deaths

8. Aside: quarterly aggregates

9. Fiscal Year aggregates

10. Calendar Year aggregate

11. Water compnies

12. This area was fed by two water companies

13. Deathrate less where clean water

16. Current medical mystery
Sudan's Luckless Children, Locked in Land of Nod, NY Times, Sept 22, 2003
Mysterious ailment among some children of Sudan
Nod, don't grow fully, die in late teens
Theories: fly bite, poison, contaminated food

17. References found on