1. Fatty Acid Synthesis
Title slide - fatty acid synthesis

2. Voet & Voet comparison of oxidation and synthesis of fatty acids
Voet & Voet comparison of oxidation and synthesis of fatty acids. They show 5 difference; Stryer has 6 differences; and I have 7 differences that I discuss in the html (web) presentation.

3. ACC, acetyl CoA carboxylase reaction. The enzyme contains biotin.

4. Enzyme activities of the fatty acid synthase.

5. Continued enzyme activities of the fatty acid synthase.

6. Again continued enzyme activities of the fatty acid synthase.

7. The final step in the fatty acid synthase reactions
The final step in the fatty acid synthase reactions. Release of palmitate.

8. The whole scheme. Fatty acid synthase functions as a dimer.

9. The structure of the carriers: 4’-phosphopantheine (carrier for biosynthesis)and CoA (carrier for catabolism).

10. The overall reaction sequence for fatty acid synthesis.

11. Close-up diagram of the various enzymatic activities in the dimer of fatty acid synthase.

12. The reaction sequence showing the involvement of the dimers.

13. Transport of acetyl groups from the mitochondria where they are formed to the cytosol where they are used for fatty acid synthesis.

14. A more detailed diagram showing sources.

15. Elongation of fatty acid from C-16 in mitochodria.

16. The desaturase reaction to form unsaturated fatty acids.