1. Synthesis of Amlodipine
2015/06/05
Jun Min Jung

2. Amlodipine
3-ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2- chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

3. Total scheme of amlodipine

4. 1

5. 2

6. 3 Knoevenagel condensation

7. 3 Knoevenagel condensation

8. 3 Knoevenagel condensation mechanism

9. 3 Knoevenagel condensation mechanism

10. 3 Knoevenagel condensation mechanism

11. 4 hantzsch dihydropyridine synthesis

12. hantzsch dihydropyridine synthesis

13. hantzsch dihydropyridine synthesis

14. hantzsch dihydropyridine synthesis

15. hantzsch dihydropyridine synthesis
calcium channel blocker (calcium antagonist), a drug used to control hypertension (high blood pressure)

16. 5