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by Kiran Musunuru, and Sekar Kathiresan

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1 by Kiran Musunuru, and Sekar Kathiresan
Surprises From Genetic Analyses of Lipid Risk Factors for Atherosclerosis by Kiran Musunuru, and Sekar Kathiresan Circulation Research Volume 118(4): February 19, 2016 Copyright © American Heart Association, Inc. All rights reserved.

2 The cumulative effects of genetic variants that raise plasma low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG) levels on the risk of myocardial infarction (MI). The cumulative effects of genetic variants that raise plasma low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG) levels on the risk of myocardial infarction (MI). SD indicates standard deviation. Kiran Musunuru, and Sekar Kathiresan Circ Res. 2016;118: Copyright © American Heart Association, Inc. All rights reserved.

3 Lipid-associated and nonlipid-associated genes identified in a genome-wide association study (GWAS) on coronary heart disease (CHD). Lipid-associated and nonlipid-associated genes identified in a genome-wide association study (GWAS) on coronary heart disease (CHD). ABCG5/G8 indicates ATP-binding cassette sub-family G member 5/8; ABO, ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase); LIPA, lipase A, lysosomal acid, cholesterol esterase; LPL, lipoprotein lipase; SH2B3, SH2B adaptor protein 3; SORT1, sortilin 1; and TCF21, transcription factor 21. Kiran Musunuru, and Sekar Kathiresan Circ Res. 2016;118: Copyright © American Heart Association, Inc. All rights reserved.

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