1. I-Flow Corporation
Who We Are

2. Overview Corporate Profile I-Flow History Traditional Pain Management
Why treat pain locally?
ON-Q* Pain Relief System
Why Clinicians Choose the ON-Q* Brand

3. Who is I-Flow?
I-Flow is the exclusive manufacturer and marketer of ON-Q* branded products
Offices in Lake Forest, CA
Manufacturing in Tijuana, Mexico
Started in 1985
Acquired by Kimberly-Clark and became a Kimberly-Clark Health Care Company in November 2009

4. Corporate Profile >125 Published & Presented Clinical Studies
Approx. >80% Market Share
ON-Q* pumps have been used in > 3 million surgeries worldwide
I-Flow Has Sold a Total of > 40 million Infusion Pumps
170 Field Sales Representatives
80 Clinical Specialists and Nurses
18 Region Business Managers and 4 Zone Directors
18 Regional Anesthesia Training Centers and Cadaver Labs
Extensive Speakers Program
Dedicated National Accounts Team
Dedicated Clinical Research & Education Team
International Presence and Distribution
National Account Purchasing Affiliation

5. I-Flow’s Product Evolution
Elastomeric technology was applied by physicians for leading edge

6. Traditional Pain Management
Patient Controlled Analgesia (PCA)
Epidural Pain Management
Oral Opioids
Non-opioid Analgesics

7. Problems Associated with Opioids that May Be Reduced or Eliminated with ON-Q* Pumps+
Nausea and Vomiting
Constipation and Ileus
Urinary Retention
Respiratory Depression
Delayed or Restricted Ambulation
Sedation
Confusion
Tolerance/Abuse
+Due to a reduction in the use of opioids

8. Local Anesthetic Pain Pump Market
ON-Q* is the global market-leading product for local anesthetic infusion devices.
ON-Q* features:
Superior pump and catheter technology
The greatest variety of pump and catheter combinations to meet the widest variety of clinical needs
Superior Value

9. Superior Value
Dedicated sales and clinical team equipped to service account needs
Sales, service, support, clinical, patient and reimbursement hotlines
PNB Specialists
Educational Programs
CPNB Educational Centers
Ultrasound Courses
Speakers Bureau
Patient Education
Clinical support materials and education
Co-op marketing/ Local PR
BAXA leasing program
Pre-fill program

10. Why treat pain locally? Systemic Narcotics Epidural Spinal PNB
Incisional

11. ON-Q* FDA Indications
Provides significantly better pain relief than narcotics alone
Significantly reduces the need for narcotics

12. ON-Q* Pain Relief System
A simple, portable, disposable pain relief system that automatically delivers a local anesthetic to or near a surgery site or near a peripheral nerve over multiple days
Provides significantly better pain relief than narcotics alone
Significantly reduces the needs for narcotics
Elastomeric & Soaker* Catheter Technology
Unique, Patented Soaker* Catheter
Antimicrobial ON-Q * SilverSoaker* Catheter

13. ON-Q* Benefits
Reduced or eliminated opioid associated side effects and complications, including:
Faster, more comfortable recovery
Quicker return to normal
bowel function, ambulation
Reduced risk of post-operative nausea and vomiting (PONV)
Reduced length of stay (LOS)
Higher patient and family satisfaction

14. Uses for ON-Q* Pumps Incisional CPNB
Used at or near the surgical site area
Catheters placed by surgeons
Used across multiple specialties, including: CV/CT, General, OB/Gyn, Bariatric, Colo-rectal, Spine, Plastics and Urology.
CPNB
Used for continuous peripheral nerve blocks (at the peripheral nerves)
Catheters placed by regional anesthesiologists
Used in orthopedic cases and some abdominal cases (TAP)
Ultrasound imaging of the targeted innervation is commonly used.

15. ON-Q* Pain Relief System
Fill port, one-way check valve
Pressure source is elastomeric with multi-layer membrane
Flow controllers:
SELECT-A-FLOW*: Variable Flow Rate
ONDEMAND*: PCA Bolus
FIXED FLOW RATE: In-line restrictor
Filter
Clamp
Sizes: 100 ml – 600 ml
Flow Rates: 0.5 ml/hr – 14 ml/hr

16. ON-Q* Elastomeric Technology

17. ON-Q* with SELECT-A-FLOW* (SAF) Controller
Developed to meet the demand for variable flow rates
Allows titration of flow rate to meet varying clinical needs
May help avoid the programming errors associated with electronic pumps

18. ON-Q* with ONDEMAND* Bolus
Allows for continuous infusion plus Patient Controlled Administration (PCA) bolus delivery
An extra 5 ml bolus can be administered by the patient as needed every 30 or 60 minutes

19. ON-Q* Pump with SAF + ONDEMAND
400 ml pump with:
SAF
ONDEMAND Bolus

21. More than 125 clinical studies
From highly reputable institutions such as:
Cleveland Clinic Florida
Jewish Hospital
Maimonides Medical Center
Medical University of South Carolina
MD Anderson Cancer Center
The University of Texas Southwestern Medical Center at Dallas
University of Southern California
University of North Carolina, Chapel Hill
Washington University, St. Louis
Yale University School of Medicine

22. Why Clinicians Choose ON-Q* Products
Wide variety of pump, catheter and accessory options
Proven technology with > 3 million surgeries worldwide
Significantly better than narcotics alone – non-systemic and avoids side effects of narcotics
Significant reduction in narcotic use – less daily consumption and less rescue medication
Patients ambulate faster with quicker return of bowel function
Reduced length of stay
Greater overall patient comfort and patient satisfaction
Simple, intuitive and safe to use – no programming, disposable
Extensive clinical data, resources and education focus

23. Questions?
Thank you!