1. Activation of the tissue factor pathway of blood coagulation in patients with chronic urticaria 
Riccardo Asero, MD, Alberto Tedeschi, MD, Raffaella Coppola, PhD, Samantha Griffini, PhD, Paolo Paparella, MD, Piersandro Riboldi, MD, Angelo V. Marzano, MD, Daniele Fanoni, PhD, Massimo Cugno, MD 
Journal of Allergy and Clinical Immunology 
Volume 119, Issue 3, Pages (March 2007)
DOI: /j.jaci
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2. Fig 1
Plasma prothrombin fragment F1+2 levels in patients and controls. Results are expressed as nmol/L, and horizontal lines represent the mean values. Mean F1+2 plasma levels were significantly higher in patients with CU (P < .001).
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3. Fig 2
Plasma D-dimer levels in patients and controls as measured by ELISA. Results are expressed as ng/mL, and horizontal lines represent the mean values. Mean D-dimer plasma levels were significantly higher in patients than in controls (P < .01).
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4. Fig 3
Plasma FXIIa levels in patients and controls. Results are expressed as ng/mL, and horizontal lines represent the mean values. No difference in mean values was observed between patients and controls.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5. Fig 4
Plasma FVIIa levels in patients and controls. Results are expressed as ng/mL, and horizontal lines represent the mean values. Mean plasma FVIIa was significantly higher in patients than in controls (P < .001).
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

6. Fig 5
Scores of tissue factor immunoreactivity in tissue samples from normal skin and urticarial skin lesions. 0, No immunoreactive cells; 1, 1-5 immunoreactive cells; 2, 6-20 immunoreactive cells; 3, >20 immunoreactive cells.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

7. Fig 6
Tissue factor immunoreactivity in urticarial skin lesion (A) and normal skin (B) (alkaline phosphatase antialkaline phosphatase method; ×100). Urticaria skin lesions display a strong expression of tissue factor by upper dermal inflammatory cells that is not present in normal skin. In contrast, normal skin appears to be completely negative for tissue factor.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions