1. Volume 40, Issue 1, Pages 1-2 (January 2014)
What Doesn’t Kill You Makes You Stronger: The Anti-inflammatory Effect of Neutrophil Respiratory Burst 
Niels Borregaard 
Immunity 
Volume 40, Issue 1, Pages 1-2 (January 2014)
DOI: /j.immuni
Copyright © 2014 Elsevier Inc. Terms and Conditions

2. Figure 1
Hypoxia Induced by Activated Neutrophils Protects Epithelial Cells
Activated neutrophils (N) infiltrate the mucus membrane during gastrointestinal inflammation. NADPH oxidase activity consumes oxygen for production of reactive oxygen species H2O2 and hypochlorous acid, OCl−. The resulting lowering of oxygen tension in epithelial cells (E) indicated by darker shading results in increased levels of hypoxia inducible factor (HIF), a transcription factor that activates transcription of genes that result in protection of the mucosal cells and reduces inflammation.
Immunity  , 1-2DOI: ( /j.immuni )
Copyright © 2014 Elsevier Inc. Terms and Conditions