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Carotid Artery Mechanical Properties of Dahl Salt-Sensitive Rats

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1 Carotid Artery Mechanical Properties of Dahl Salt-Sensitive Rats
by Athanase Benetos, Hervé Bouaziz, Pierre Albaladejo, David Guez, and Michel E. Safar Hypertension Volume 25(2): February 1, 1995 Copyright © American Heart Association, Inc. All rights reserved.

2 Diagram of the experimental model for in situ evaluation of the pressure-volume curve in isolated carotid arteries. Diagram of the experimental model for in situ evaluation of the pressure-volume curve in isolated carotid arteries. P indicates pressure. Athanase Benetos et al. Hypertension. 1995;25: Copyright © American Heart Association, Inc. All rights reserved.

3 Line graphs show carotid artery pressure-volume curves in untreated (top) and indapamide-treated (bottom) rats. Line graphs show carotid artery pressure-volume curves in untreated (top) and indapamide-treated (bottom) rats. DSL indicates Dahl salt-sensitive rats receiving 0.4% NaCl; DSH, Dahl salt-sensitive rats receiving 7% NaCl; DRL, Dahl salt-resistant rats receiving 0.4% NaCl; and DRH, Dahl salt-resistant receiving 7% NaCl. *P<.01, Dahl salt-sensitive versus Dahl salt-resistant as shown by two-way ANOVA (strain, NaCl diet). Athanase Benetos et al. Hypertension. 1995;25: Copyright © American Heart Association, Inc. All rights reserved.

4 Bar graph shows effects of indapamide treatment on systemic operating carotid compliance in rat groups (see definitions in Fig 2 legend). Bar graph shows effects of indapamide treatment on systemic operating carotid compliance in rat groups (see definitions in Fig 2 legend). Filled bars indicate untreated; open bars, indapamide treated *P<.05, **P<.01, with vs without indapamide treatment. Athanase Benetos et al. Hypertension. 1995;25: Copyright © American Heart Association, Inc. All rights reserved.


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