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Volume 135, Issue 5, Pages (November 2008)

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Presentation on theme: "Volume 135, Issue 5, Pages (November 2008)"— Presentation transcript:

1 Volume 135, Issue 5, Pages 1510-1516 (November 2008)
Oral Budesonide for Maintenance Treatment of Collagenous Colitis: A Randomized, Double-Blind, Placebo-Controlled Trial  Stephan Miehlke, Ahmed Madisch, Birgit Bethke, Andrea Morgner, Eberhard Kuhlisch, Christine Henker, Gerfried Vogel, Matthias Andersen, Eberhard Meier, Gustavo Baretton, Manfred Stolte  Gastroenterology  Volume 135, Issue 5, Pages (November 2008) DOI: /j.gastro Copyright © 2008 AGA Institute Terms and Conditions

2 Figure 1 Study design. HRQOL, health-related quality of life.
Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions

3 Figure 2 Flow of patients through the study. *Two budesonide patients in remission declined colonoscopy; therefore, colonoscopies were performed in 15 and 8 patients receiving budesonide and placebo, respectively. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions

4 Figure 3 Kaplan–Meier curves of patients with relapse of collagenous colitis during maintenance therapy with oral budesonide 6 mg once daily or placebo. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions

5 Figure 4 Proportions of patients with clinical remission of collagenous colitis at months 2, 4, and 6 of maintenance therapy with oral budesonide 6 mg once daily or placebo. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions

6 Figure 5 Mean sIBDQ domain scores at baseline and after 6 weeks of induction therapy with oral budesonide 9 mg once daily in patients with collagenous colitis. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions


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