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Value-Based Hypothesis Testing for Cardiac Device Clinical Trials

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Presentation on theme: "Value-Based Hypothesis Testing for Cardiac Device Clinical Trials"— Presentation transcript:

1 Value-Based Hypothesis Testing for Cardiac Device Clinical Trials
by Donald E. Cutlip, and Daniel B. Kramer Circ Cardiovasc Interv Volume 9(5):e003627 April 19, 2016 Copyright © American Heart Association, Inc. All rights reserved.

2 Four quadrants of a quality to cost relationship.
Four quadrants of a quality to cost relationship. Quadrant D represents ultimate value based on higher quality at reduced cost but is unlikely to be achieved by most new technology. Quadrant A is unacceptably poor value because of reduced quality at higher cost. Quadrants B and C are possible areas for a value-based hypothesis with constraints of acceptable cost thresholds for increasing quality (hatched area B) and acceptable quality reduction for proportionate cost savings (hatched area C). Donald E. Cutlip, and Daniel B. Kramer Circ Cardiovasc Interv. 2016;9:e003627 Copyright © American Heart Association, Inc. All rights reserved.


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