1. Gene therapy: efficient targeting of hematopoietic stem cells
by Stefan Karlsson
Blood
Volume 106(10):
November 15, 2005
©2005 by American Society of Hematology

2. Lentiviral vector particles (HIV-1) display recombinant membrane envelope proteins containing stem cell factor (SCF) and TPO that can specifically target the vector particles to hematopoietic stem cells (HSCs) expressing the c-kit and c-mpl r...
Lentiviral vector particles (HIV-1) display recombinant membrane envelope proteins containing stem cell factor (SCF) and TPO that can specifically target the vector particles to hematopoietic stem cells (HSCs) expressing the c-kit and c-mpl receptors for SCF and TPO, respectively. All vector particles contain the VSV-G envelope protein, which binds to phospholipids in cellular membranes. Illustration by Marie Dauenheimer.
Stefan Karlsson Blood 2005;106:3333
©2005 by American Society of Hematology