1. DSS 2011-Case 5 Sandra L. Cottingham, MD, PhD
Spectrum Health Hospitals and
Helen DeVos Children’s Hospital
Grand Rapids, MI

2. History 11-year old male presented with new onset of seizures.
Past medical history is significant for migraine headaches since age 5, increasing in frequency and severity over the past three weeks.
In addition there was a history of hydrocephalus and Chiari 1 malformation diagnosed at 9 months of age.
No findings of neurofibromatosis.
His last MRI performed at age 6 was noted to be “stable.”

3. MRI at presentation

7. Diagnosis(es)?

8. Ki-67 immunohistochemistry

9. Diagnoses
Dysembryoplastic neuroepithelial tumor
Meningioangiomatosis

10. References MA and oligodendroglioma DSS 2011-4
Lopez JI, Ereno C, Oleaga L, Areitio E. Meningioangiomatosis and oligodendroglioma in a 15 year old boy. Arch Pathol Lab Med :
DSS
Unpublished case from Spectrum Health/HDVCH

11. 2008 HDVCH case 13 year old girl Presented with seizures
Cystic temporal lobe lesion

14. Association Neurofibromatosis? Coincidence?
Acknowledgement: Thanks to Dr. Peter Burger who reviewed this case.