3. Sites of Action in Coagulation System Novel Factor Xa and DT Inhibitors

4. Brief Overview of NOACs

5. NOACs Important Comparative Features

7. Effect on NOAC Plasma Levels from D-D Interactions, and Recommendations

9. Sites of Action in Coagulation System Novel Factor Xa and DT Inhibitors

10. Brief Overview of NOACs

11. Ethnic Differences in Rate of ICH

12. Estimated Levels of Exposure in White and Japanese Patients

15. Primary Efficacy End Point (Stroke/SEE) mITT Population While on Treatment

16. Main Safety Results Safety Cohort on Treatment

18. Lower NOAC Dose Clinical Implications

19. Incidence of Stroke or Systemic Embolism

20. Abbreviations

21. Abbreviations (cont)

22. Abbreviations (cont)

23. References

24. References (cont)

25. References (cont)

26. References (cont)