1. Effect of Low Cholesterol on Steroid Hormones and Vitamin E Levels
by Arman Qamar, and Deepak L. Bhatt
Circulation Research
Volume 117(8):
September 25, 2015
Copyright © American Heart Association, Inc. All rights reserved.

2. The schematic demonstrates the mechanism of low-density lipoprotein (LDL) cholesterol reduction by proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition, the sources of hepatic cholesterol, and the role of cholesterol as a precursor for the synthesis of various metabolites, including steroid hormones.
The schematic demonstrates the mechanism of low-density lipoprotein (LDL) cholesterol reduction by proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition, the sources of hepatic cholesterol, and the role of cholesterol as a precursor for the synthesis of various metabolites, including steroid hormones. LDL-R indicates LDL receptor; and VLDL, very low-density lipoprotein.
Arman Qamar, and Deepak L. Bhatt Circ Res. 2015;117:
Copyright © American Heart Association, Inc. All rights reserved.