1. *** *** *** *** *** *** Supplemental Fig. 1 A B N = 27 N = 15
300
N = 27
TG (Seq.Test)
250
TG (OTT)
200
***
***
Glucose (Seq.Test)
TG, Glucose (mg/dl), Insulin (µIU/ml)
150
Glucose (OTT)
100
Insulin (Seq.Test)
***
*** 50
Insulin (OTT) 0h 3h 4h 5h B
300
N = 15
***
***
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TG (Seq.Test)
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Glucose (OGT)
Glucose (Seq.Test)
TG, Glucose (mg/dl), Insulin (µIU/ml)
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TG (OGT)
Insulin (OGT)
Insulin (Seq.Test)
100 50 0h 3h 4h 5h
Suppl. Fig. 1 The sequential test protocol (glucose challenge 3 hours after triglyceride challenge) was validated in patients with clinically stable CAD by intra-individual comparisons of the individual test components (OTT or OGT) with the combined test on consecutive days. (A) Effects of the OTT compared to the sequential protocol in 27 patients and (B) effects of the OGT compared to the sequential protocol in 15 patients on serum concentrations of triglycerides, glucose and insulin; ***p<0.001 vs. corresponding parameter of the other test (ANOVA).

2. Supplemental Fig. 2
Suppl. Fig. 2 Design of the Homburg Cream & Sugar study and metabolic test protocol