Presentation is loading. Please wait.

Presentation is loading. Please wait.

Vegetal RNAs antagonise the dorsalising and BMP-inhibiting activity of Vrtn. Vegetal RNAs antagonise the dorsalising and BMP-inhibiting activity of Vrtn.

Published byHelga Clausen Modified over 6 years ago

Similar presentations

Presentation on theme: "Vegetal RNAs antagonise the dorsalising and BMP-inhibiting activity of Vrtn. Vegetal RNAs antagonise the dorsalising and BMP-inhibiting activity of Vrtn."— Presentation transcript:

1 Vegetal RNAs antagonise the dorsalising and BMP-inhibiting activity of Vrtn.
Vegetal RNAs antagonise the dorsalising and BMP-inhibiting activity of Vrtn. (A) Western blotting at 50% epiboly shows the rescue of P-Smad1/5/8 levels in Vrtn-overexpressing embryos by vegetal RNAs from the two- to four-cell stage. (B) P-Smad1/5/8 level is normalised to β-actin and quantified with respect to uninjected embryos. Data are mean±s.d. from four independent experiments. (C) Western blotting shows the temporal regulation of Vrtn activity by vegetal RNAs. (D) Quantification of P-Smad1/5/8 level. Vegetal RNAs from 64- or 1000-cell stages show no effect on Vrtn-inhibited P-Smad1/5/8 levels. Data are mean±s.d. from three independent experiments. (E,F) Representative embryos at 24 hpf and statistical analysis show that vegetal RNAs counterbalance Vrtn-mediated dorsalisation. Numbers at the top indicate total embryos from two independent experiments. Scale bar: 200 µm. Ming Shao et al. Development 2017;144: © Published by The Company of Biologists Ltd

Download ppt "Vegetal RNAs antagonise the dorsalising and BMP-inhibiting activity of Vrtn. Vegetal RNAs antagonise the dorsalising and BMP-inhibiting activity of Vrtn."

Similar presentations

inhibits BMP signalling.

inhibits BMP signalling.
Mitochondria localize to both the front and the rear of neutrophils.

Mitochondria localize to both the front and the rear of neutrophils.
Identification of vegetally localised vrtn transcripts.

Identification of vegetally localised vrtn transcripts.
SESN2 expression in lungs from healthy donors, habitual smokers without COPD and individuals with late-stage COPD. (A) Representative western blots of.

SESN2 expression in lungs from healthy donors, habitual smokers without COPD and individuals with late-stage COPD. (A) Representative western blots of.
Vrtn functions as a transcriptional repressor.

Vrtn functions as a transcriptional repressor.
Scanning electron microscopy analysis of EGK-I to -V chick embryos.

Scanning electron microscopy analysis of EGK-I to -V chick embryos.
Fig. 1. Representative images of the four cell lines using fluorescence microscopy. Representative images of the four cell lines using fluorescence microscopy.

Fig. 1. Representative images of the four cell lines using fluorescence microscopy. Representative images of the four cell lines using fluorescence microscopy.
Fig. 1. Chlamydia infection causes elevated levels of sortilin.

Fig. 1. Chlamydia infection causes elevated levels of sortilin.
Fig. 4. smc3 regulates the expression of cx43 in regenerating fins.

Fig. 4. smc3 regulates the expression of cx43 in regenerating fins.
Fig. 4. Abdominal aortic aneurysm formation in zebrafish embryos following treatment with Angiotensin II or snuff extract. Abdominal aortic aneurysm formation.

Fig. 4. Abdominal aortic aneurysm formation in zebrafish embryos following treatment with Angiotensin II or snuff extract. Abdominal aortic aneurysm formation.
Fig. 2. Morphological changes of cultured adherent fibroblastic cells after OA treatment related to actin microfilament reorganization.(A) Cells observed.

Fig. 2. Morphological changes of cultured adherent fibroblastic cells after OA treatment related to actin microfilament reorganization.(A) Cells observed.
Fig. 4. Expression of miR-2 family mediates tissue growth of Hippo pathway.(A) Photomicrographs of adult wings of the indicated genotype. Expression of.

Fig. 4. Expression of miR-2 family mediates tissue growth of Hippo pathway.(A) Photomicrographs of adult wings of the indicated genotype. Expression of.
Fig. 1. Mitochondrial internalization in cardiomyocytes.

Fig. 1. Mitochondrial internalization in cardiomyocytes.
Fig. 3. Inactivation of the Wnt/β-catenin signaling pathway inhibited cell proliferation and induced apoptosis in A549 and SPC-A-1 cells. Inactivation.

Fig. 3. Inactivation of the Wnt/β-catenin signaling pathway inhibited cell proliferation and induced apoptosis in A549 and SPC-A-1 cells. Inactivation.
TP53 western blot of primary cultured tail cells from both wild-type (WT) and Tp53Δ11/Δ11 (−/−) rats. TP53 western blot of primary cultured tail cells.

TP53 western blot of primary cultured tail cells from both wild-type (WT) and Tp53Δ11/Δ11 (−/−) rats. TP53 western blot of primary cultured tail cells.
Tomoregulin-1 inhibits the TGFβ non-canonical (TAK1-JNK) pathways after pressure overload. Tomoregulin-1 inhibits the TGFβ non-canonical (TAK1-JNK) pathways.

Tomoregulin-1 inhibits the TGFβ non-canonical (TAK1-JNK) pathways after pressure overload. Tomoregulin-1 inhibits the TGFβ non-canonical (TAK1-JNK) pathways.
Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse myocardium. Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse.

Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse myocardium. Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse.
Fig. 7. E2F1 acetylation in A1/A2-KO MEFs

Fig. 7. E2F1 acetylation in A1/A2-KO MEFs
Overexpression of Nedd4 is able to rescue miR-1-mediated actin fiber disarray in larval hearts. Overexpression of Nedd4 is able to rescue miR-1-mediated.

Overexpression of Nedd4 is able to rescue miR-1-mediated actin fiber disarray in larval hearts. Overexpression of Nedd4 is able to rescue miR-1-mediated.
Fig. 4. Non-autonomous rescue of puc expression in DME cells

Fig. 4. Non-autonomous rescue of puc expression in DME cells

Similar presentations

Ads by Google