1. Prospective associations of plasma phospholipid trans/trans-18:2 with total mortality, CVD and CHD before and after mutual adjustment without correction of laboratory drift.
Prospective associations of plasma phospholipid trans/trans-18:2 with total mortality, CVD and CHD before and after mutual adjustment without correction of laboratory drift. Black triangles indicate multivariate-adjusted hazard ratios comparing adults in the top quintile category to adults in the bottom quintile category for t/t-18:2 fatty acid levels, before mutual adjustment for the 5 TFAs and without correction of laboratory drift; red diamonds, after mutual adjustment for the 5 TFAs and without correction of laboratory drift. Error bars represent 95% CI. All risk estimates were adjusted for age, sex, race, education, enrollment site, diabetes, hypertension, smoking, alcohol consumption, physical activity, BMI, waist circumference, dietary saturated fat, dietary monounsaturated fat, dietary fiber, plasma phospholipid EPA+DHA, plasma phospholipid linoleic acid. *P-trend<0.05 across quintiles. BMI indicates body–mass index; CHD, coronary heart disease; CVD, cardiovascular disease; EPA+DHA, EPA+DHA, eicosapentaenoic acids plus docosahexaenoic acids; TFA, trans–fatty acid.
Qianyi Wang et al. J Am Heart Assoc 2014;3:e000914
© 2014 Qianyi Wang et al.