1. Device for Measuring Esophageal Tissue Compliance
TEAM MEMBERS:
Kristen Seashore Janelle Anderson Lynn Murray Chris Goplen
CLIENT:
Mark Reichelderfer, M.D. Department of Gastoenterology
Eric Gaumnitz, M.D. Deepak Gopal, M.D. Patrick Pfau, M.D.
ADVISOR:
Professor Naomi Chesler

2. Background Information
Stricture = scar tissue build up
Causes: Achalasia, reflux, cancer…
Treatments: surgery or dilation
Want to know stricture characteristics
Compliance, size, length, location, number
Balloon dilatation of esophageal stricture

3. Esophageal Stricture Compliance
Problem Statement
“Smart Balloon” Project
Computer interface
Pressure vs. Volume curve
Tissue compliance
Feedback for doctor
Prevent esophageal perforation
Chance to abort procedure
Speed up procedures
Reduce number of procedures
Testing
Esophageal Stricture Compliance
Pressure (atm)
High compliance
Low compliance
Volume (mL)

4. Current Devices No comparable devices Radiographs
Liquid bolus, solid spheres
Barium, film, and ruler
Balloon, Syringe, Dispenser
Balloon and Syringe Device

5. Competition Limited due to specificity Only previous work from 2002
No funding

6. Design Constraints Low cost Reusable Easy to Use Safe Accurate Durable
Approval for testing

7. Problem Overview Reduce the frequency of esophageal perforations
Safe, Easy to learn and use
Provide accurate and reliable information
Replaceable, low-cost balloon
Reusable inflating device
Speed up and reduce number of procedures

8. Design 1: Linear Position Transducer
Transducer measures linear distance plunger moves
Use distance to convert to volume
Second transducer records balloon pressure

9. Design 1: Pros/Cons Pros Minimal adjustment to current device
Easy to use
Least expensive
Produces accurate data
Feasible to construct
Cons
Linear position transducer may be bulky

10. Design 2: Flow Meter Attach flow meter to record volume
Replace pressure gauge with transducer to directly record pressure

11. Design 2: Pros/Cons Pros Cons
Small device with only a flow meter attached
Easy to use
Produces accurate data
Cons
Not very durable
Not feasible unless flow meter is small

12. Design 3: T-Piece and Laser
Laser to measure distance pump moves
Convert distance to volume
“T-piece” wire and pressure transducer

13. Design 3: Pros/Cons Pros Cons Produces accurate data
No tampering with pressure gauge
Cons
Most expensive design
Less durable
Not very feasible

14. Feature (Possible Points)
Design Matrix
Feature (Possible Points)
Design 1
Design 2
Design 3
Size (5) 4 5 3
Ease of Use (6) 6
Cost (12) 9 2
Accuracy (20) 15
Reproducibility (8) 7
Durability (10) 8
Aesthetics (4)
Feasibility (15) 14
Safety (20) 20 10
TOTALS: 86 74 55

15. Future Work Obtain materials
Separate balloon and esophageal compliance
Learn more about circuitry
Write software program using LabView
Testing on animals

16. References http://www.endoatlas.com/es_es_03.html
htt[p://
Dyet, J. et al Radiological Measurement of Oesophageal Stricture Diameter. Clinical Radiology, 34:

17. Questions?