1. Membranes
Epithelial membrane- combination of epithelial layer and underlying connective tissue

2. Mucous Membrane (Mucosae)
Line cavities that open to exterior (i.e. GI tract)
Connective tissue layer called lamina propria
Secretes mucous

3. Serous Membrane Also known as serosa
Lines body cavity not open to exterior (pleura, pericardium, peritoneum)- parietal and visceral
Secrete serous fluid

4. Cutaneous Membrane
The skin

5. Synovial Membrane Line joint cavities Do not contain epithelium
Secrete synovial fluid

6. Integumentary System
Cutaneous membrane
Largest organ
16% body weight
2 square meters area
The Skin

8. 4 types of cells Keratinocytes: 90% Langerhans cells Merkel cells
produce keratin and lamellar granules
Langerhans cells
mount immune response
Merkel cells
contact sensory neurons
Melanocytes: 8%
produce pigments to absorb
UV radiation

10. produce new keratinocytes/ tonofilaments for attachment
Stratum basale:
produce new keratinocytes/
tonofilaments for attachment

11. Stratum spinosum:
tonofilaments for strength and stability

12. Stratum granulosum:
flattened dying cells- release
keratin and lamellar granules

13. Stratum lacidum:
only in thick layers
flattened dead cells

14. Stratum corneum:
flattened, dead, continually shed

15. Skin Graft

16. Psoriasis

17. Dermis

18. Striae: Tears in Dermis
(stretch marks)

19. Epidermal Ridges

20. Tanning
Skin
colors
Freckles
Melanin
Moles

21. Vitiligo
Albinism

22. McCune Albright Syndrome
Link

23. Tattooing
Currently there are two men who are nearly tied for the Most Tattoo Man record. One is a retired military man who lives in Scotland named Tom Leppard, who just happens to have 99.9% of his body covered in leopard spots. He has no other tattoo designs other than this all-covering pattern which is only absent from the insides of his ears and between his toes.

24. Elaine Davidson of Edinburgh, Scotland, has acquired a record 462 body piercings since January 1997, 192 of which are on her head.

25. Hair anatomy

26. lanugo
vellus
terminal hair

27. Sebaceous gland-
secretes oil to coat
hair and skin
Sudoriferous glands-
secrete sweat
Eccrine- throughout
skin- regulate temp/
eliminate some
Waste
Apocrine- armpits,
groin, breast, face-
stimulated with
stress

28. Ceruminus Gland
(earwax)

29. Nails
Tightly packed, hard, dead,
keratinized epidermal cells

30. sensations
protection
absorption
blood reservoir
thermoregulation

31. Figure 1. Acute wound healing in porcine skin at 3 days (upper left panel), 5 days
(upper right panel),7 days (lower left panel) and 10 days (lower right panel). An organized
fibrin clot is observed at 3 days, but there is no evidence of new dermal tissue healing.
In contrast, at 5 days connective tissue cells (fibroblasts) and blood vessels have filled
the defect. Reorgan- zation of the tissue has occurred over the next week (days 7 and 10).

32. Ecoderm
(epidermis)
Mesoderm
(dermis)

33. Aging Mostly dermis- loss of collagen, elasticity of
fibers decreases, decreased immune
response, less oil and sweat, less
melanocytes, skin thins