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Targeting the PARP DNA repair pathway enhanced cytotoxicity induced by chemotherapy. Targeting the PARP DNA repair pathway enhanced cytotoxicity induced.

Published byKalevi Lahtinen Modified over 6 years ago

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Presentation on theme: "Targeting the PARP DNA repair pathway enhanced cytotoxicity induced by chemotherapy. Targeting the PARP DNA repair pathway enhanced cytotoxicity induced."— Presentation transcript:

1 Targeting the PARP DNA repair pathway enhanced cytotoxicity induced by chemotherapy.
Targeting the PARP DNA repair pathway enhanced cytotoxicity induced by chemotherapy. A, Dose-response curves for IDH1 mutant cells treated with TMZ and Ola (n = 3). B, Annexin-V apoptosis analysis demonstrated the potentiation effect of Ola for TMZ chemotherapy. C, Quantification of apoptotic cells in IDH1 mutant cells treated with TMZ and/or Ola. Yanxin Lu et al. Cancer Res 2017;77: ©2017 by American Association for Cancer Research

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