1. Chapter 9
MITOSIS
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

2. Copyright © The McGraw-Hill Companies, Inc
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

3. 9.1 The Cell Cycle
**Orderly set of steps between eukaryotic cell divisions Why do Cells Divide? Growth Reproduction    (in single celled organisms) Repair

4. a. ________________ b. ________________ c. _________________
d.  _________________
e.  _________________
f.  __________________
Pg 81 f.

5. Control of the Cell Cycle 
G1 Checkpoint - Check to see if DNA is damagedG2 Checkpoint - Check to see if DNA is replicated properlyM Checkpoint - spindle assembly checkpoint, check for alignment of chromosomes 
Apoptosis - programmed cell death, if any of the checks fail

6.  9.2 Mitosis & Cytokinesis 
Mitosis - The division of the nucleus that results in identical complete copies of chromosmes packaged into two new nuclei
Cytokinesis - The division of the cytoplasm that results in two daughter cells

7. Interphase • Prophase • Metaphase • Anaphase • Telophase
IPMAT

9. Interphase:  Resting
Prophase: Chromosomes visible, spindle forms as centrioles move
Metaphase:  Chromosomes line up along equator
Anaphase:  Chromatids separate
Telophase:  Nuclear membrane forms on each side, cytokinesis begins

10. **In plant cells, cytokinesis begins when a new cell wall forms between the two new cells. **In animal cells, the two new cells pinch and pull apart

11. 9.3 The Cell Cycle and Cancer
neoplasm: abnormal growth of cells
benign: non-cancerous
malignant: cancerous
Cancer: cellular growth disorder that results from the mutation of genes that regulate the cell cycle
Cancer cells
lack differentiation
have abnormal nuclei
form tumors
undergo metastasis & angiogenesis 

13. Mitosis produces 2 daughter cells
The two daughter cells contain the exact same number of chromosomes as the original parent cell
Daughter cells are DIPLOID

14. HeLa Cells Article on Henrietta Lacks
A HeLa cell (also Hela or hela cell) is a cell type in an immortal cell line used in scientific research. It is the oldest and most commonly used human cell line.
The line was derived from cervical cancer cells taken from Henrietta Lacks, a patient who eventually died of her cancer on October 4, 1951.

15. Name the phases starting at the top.

16. Name the phase
Identify X
Identify Y

17. 5. Name the phase

18. 6. Name the phase

19. 10. In humans, each cell (except sex cells) has how many chromosomes
11.  After mitosis, how many daughter cells are produced?  _______
12.  After mitosis (in a human cell), each daughter cell has how many chromosomes? _____
13.  How many phases are in MITOSIS? ___________
14.  Which phase of the cell cycle is the longest?  _________
15.  During which phase does cytokinesis begin?  __________