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Bariatric Surgery Christopher Joyce, MD, FACS President
Illinois Association of Bariatric Surgeons 9/22/2018
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Overview Obesity problem in America Bariatric Surgery overview
9/22/2018 Obesity problem in America Bariatric Surgery overview Surgical treatments Direct Cardiac Effects Impact on Metabolic syndrome Impact on Mortality
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What Is Morbid Obesity? 9/22/2018 Clinically severe obesity at which point serious medical conditions occur as a direct result of the obesity Defined as >200% of ideal weight, >100 lb overweight, or a body mass index of ≥40
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Body Mass Index (BMI) W.H.O. Classification BMI Ideal Weight 18-24.9
9/22/2018 W.H.O. Classification BMI Ideal Weight Overweight Moderate Obesity (Class I) Severe Obesity (Class II) Morbid Obesity (Class III) (Super Obesity) 50+
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Do You Know Your Own BMI? Weight (lbs) Height 9/22/2018 5'4" 5'2" 5'0"
5'10" 5'8" 5'6" 6'0" 6'2" 120 130 150 160 170 180 190 200 210 220 230 240 250 140 260 270 280 290 300 6'4"
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NIH Criteria for Bariatric Surgery
9/22/2018 BMI > 40 BMI > 35 with comorbidities* *Includes sleep apnea, cardiomyopathy, diabetes mellitus, hypertension, dyslipidemia, DJD *BCBS of IL and Anthem (IN) require 2, all other insurers require 1
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Obesity Trends* Among U.S. Adults BRFSS, 1990
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14%
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Obesity Trends* Among U.S. Adults BRFSS, 1991
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19%
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Obesity Trends* Among U.S. Adults BRFSS, 1992
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19%
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Obesity Trends* Among U.S. Adults BRFSS, 1993
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19%
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Obesity Trends* Among U.S. Adults BRFSS, 1994
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19%
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Obesity Trends* Among U.S. Adults BRFSS, 1995
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19%
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Obesity Trends* Among U.S. Adults BRFSS, 1996
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19%
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Obesity Trends* Among U.S. Adults BRFSS, 1997
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19% ≥20%
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Obesity Trends* Among U.S. Adults BRFSS, 1998
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19% ≥20%
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Obesity Trends* Among U.S. Adults BRFSS, 1999
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19% ≥20%
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Obesity Trends* Among U.S. Adults BRFSS, 2000
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19% ≥20%
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Obesity Trends* Among U.S. Adults BRFSS, 2001
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19% %–24% ≥25%
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Multi-disciplinary Team
9/22/2018
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Figure 1. Obesity, cardiac failure, and the beneficial role of bariatric surgery.
Figure 1. Obesity, cardiac failure, and the beneficial role of bariatric surgery. RV indicates right ventricular; LV, left ventricular. Ashrafian H et al. Circulation 2008;118: Copyright © American Heart Association
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Figure 2. Mechanisms of atherosclerosis and the beneficial role of bariatric surgery.
Figure 2. Mechanisms of atherosclerosis and the beneficial role of bariatric surgery. ICAM-1 indicates intercellular adhesion molecule-1; PAI-1, plasminogen activator inhibitor-1. Ashrafian H et al. Circulation 2008;118: Copyright © American Heart Association
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Severe Cardiomyopathy
9/22/2018 EF<35%(n=14) EF improved from 23% to 6 mos. (p=0.4) NYHA dropped by 1 Class 50% EBWL Decrease in BMI from 51 to 37 McCloskey, SOARD 2007 Pitt.
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Improved Cardiac Function: Utah Obesity Study
9/22/2018 Owan, JACC Salt Lake
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Obesity, T2DM, and Other Comorbidities
9/22/2018 Prospective Cohort Study: Sleeve vs Medical Rx 80% vs 0% Resolution of Diabetes 80% vs 0% Resolution of OSA Hypertension and dyslipidemia medications cut in half Leonnetti ARCH SURG, 8/12
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9/22/2018
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Leonnetti ARCH SURG, 8/12 9/22/2018
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Natural history and metabolic consequences of morbid obesity for patients denied coverage for bariatric surgery 189 patients denied, 587 LRYGB 3-year follow-up BMI increased from 47.3 to 46.8 in denied pts. BMI decreased from 48.5 to 30.5 in bypass pts. New-onset DM, HTN, OSA, GERD, and dyslipidemias higher in denied group(p<.001) Harakeh AB. SOARD 2010,591-6
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Fear of Bariatric Surgery
9/22/2018 Bariatric Surgery (1035 Patients) Controls (5746 patients) n % P Value CV Event 49 4.7 1530 26.7 0.001 Cancer 21 2.0 487 8.5 DM 98 9.47 1566 27.3 Inf. Disease 90 8.7 2140 37.3 Death 7 0.68 354 6.2 Christou et al. McGill Univ Annals of Surgery, Sept. 2004
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Surgery Decreases Mortality
9/22/2018 Author Decreased Mortality Mean f/u (yrs) Christou Ann Surg 2004 89% 5 Flum JACS 2004 40% 4.4 Bussetto SOARD 2008 60% Sjostrom NEJM 2007 30% 10.9 Adams 7.1
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40% reduction in death from any cause Disease Specific Mortality
9/22/2018 Long Term Mortality (retrospective study ) 9949 surgical patients matched to 9628 non-surgical patients 40% reduction in death from any cause Disease Specific Mortality 56% reduction from CAD 92% reduction from DM 60% reduction from cancer Long Term Mortality (retrospective study ) 9949 patients in surgery arm matched to 9628 non-surgical
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Walk in the shoes of the morbidly obese person for one day and you will understand their suffering.
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Questions???
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