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Bariatric Surgery Christopher Joyce, MD, FACS President

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1 Bariatric Surgery Christopher Joyce, MD, FACS President
Illinois Association of Bariatric Surgeons 9/22/2018

2 Overview Obesity problem in America Bariatric Surgery overview
9/22/2018 Obesity problem in America Bariatric Surgery overview Surgical treatments Direct Cardiac Effects Impact on Metabolic syndrome Impact on Mortality

3 What Is Morbid Obesity? 9/22/2018 Clinically severe obesity at which point serious medical conditions occur as a direct result of the obesity Defined as >200% of ideal weight, >100 lb overweight, or a body mass index of ≥40

4 Body Mass Index (BMI) W.H.O. Classification BMI Ideal Weight 18-24.9
9/22/2018 W.H.O. Classification BMI Ideal Weight Overweight Moderate Obesity (Class I) Severe Obesity (Class II) Morbid Obesity (Class III) (Super Obesity) 50+

5 Do You Know Your Own BMI? Weight (lbs) Height 9/22/2018 5'4" 5'2" 5'0"
5'10" 5'8" 5'6" 6'0" 6'2" 120 130 150 160 170 180 190 200 210 220 230 240 250 140 260 270 280 290 300 6'4"

6 NIH Criteria for Bariatric Surgery
9/22/2018 BMI > 40 BMI > 35 with comorbidities* *Includes sleep apnea, cardiomyopathy, diabetes mellitus, hypertension, dyslipidemia, DJD *BCBS of IL and Anthem (IN) require 2, all other insurers require 1

7 Obesity Trends* Among U.S. Adults BRFSS, 1990
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14%

8 Obesity Trends* Among U.S. Adults BRFSS, 1991
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19%

9 Obesity Trends* Among U.S. Adults BRFSS, 1992
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19%

10 Obesity Trends* Among U.S. Adults BRFSS, 1993
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19%

11 Obesity Trends* Among U.S. Adults BRFSS, 1994
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19%

12 Obesity Trends* Among U.S. Adults BRFSS, 1995
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19%

13 Obesity Trends* Among U.S. Adults BRFSS, 1996
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19%

14 Obesity Trends* Among U.S. Adults BRFSS, 1997
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19% ≥20%

15 Obesity Trends* Among U.S. Adults BRFSS, 1998
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19% ≥20%

16 Obesity Trends* Among U.S. Adults BRFSS, 1999
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19% ≥20%

17 Obesity Trends* Among U.S. Adults BRFSS, 2000
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19% ≥20%

18 Obesity Trends* Among U.S. Adults BRFSS, 2001
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% %–14% %–19% %–24% ≥25%

19 Multi-disciplinary Team
9/22/2018

20

21 Figure 1. Obesity, cardiac failure, and the beneficial role of bariatric surgery.
Figure 1. Obesity, cardiac failure, and the beneficial role of bariatric surgery. RV indicates right ventricular; LV, left ventricular. Ashrafian H et al. Circulation 2008;118: Copyright © American Heart Association

22 Figure 2. Mechanisms of atherosclerosis and the beneficial role of bariatric surgery.
Figure 2. Mechanisms of atherosclerosis and the beneficial role of bariatric surgery. ICAM-1 indicates intercellular adhesion molecule-1; PAI-1, plasminogen activator inhibitor-1. Ashrafian H et al. Circulation 2008;118: Copyright © American Heart Association

23 Severe Cardiomyopathy
9/22/2018 EF<35%(n=14) EF improved from 23% to 6 mos. (p=0.4) NYHA dropped by 1 Class 50% EBWL Decrease in BMI from 51 to 37 McCloskey, SOARD 2007 Pitt.

24 Improved Cardiac Function: Utah Obesity Study
9/22/2018 Owan, JACC Salt Lake

25 Obesity, T2DM, and Other Comorbidities
9/22/2018 Prospective Cohort Study: Sleeve vs Medical Rx 80% vs 0% Resolution of Diabetes 80% vs 0% Resolution of OSA Hypertension and dyslipidemia medications cut in half Leonnetti ARCH SURG, 8/12

26 9/22/2018

27 Leonnetti ARCH SURG, 8/12 9/22/2018

28 Natural history and metabolic consequences of morbid obesity for patients denied coverage for bariatric surgery 189 patients denied, 587 LRYGB 3-year follow-up BMI increased from 47.3 to 46.8 in denied pts. BMI decreased from 48.5 to 30.5 in bypass pts. New-onset DM, HTN, OSA, GERD, and dyslipidemias higher in denied group(p<.001) Harakeh AB. SOARD 2010,591-6

29 Fear of Bariatric Surgery
9/22/2018 Bariatric Surgery (1035 Patients) Controls (5746 patients) n % P Value CV Event 49 4.7 1530 26.7 0.001 Cancer 21 2.0 487 8.5 DM 98 9.47 1566 27.3 Inf. Disease 90 8.7 2140 37.3 Death 7 0.68 354 6.2 Christou et al. McGill Univ Annals of Surgery, Sept. 2004

30 Surgery Decreases Mortality
9/22/2018 Author Decreased Mortality Mean f/u (yrs) Christou Ann Surg 2004 89% 5 Flum JACS 2004 40% 4.4 Bussetto SOARD 2008 60% Sjostrom NEJM 2007 30% 10.9 Adams 7.1

31 40% reduction in death from any cause Disease Specific Mortality
9/22/2018 Long Term Mortality (retrospective study ) 9949 surgical patients matched to 9628 non-surgical patients 40% reduction in death from any cause Disease Specific Mortality 56% reduction from CAD 92% reduction from DM 60% reduction from cancer Long Term Mortality (retrospective study ) 9949 patients in surgery arm matched to 9628 non-surgical

32 Walk in the shoes of the morbidly obese person for one day and you will understand their suffering.

33 Questions???


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