1. Compound
IC50 [nM]
α5β1
αvβ3
References
(ref.; Compound name) 1
2,3
3000
Heckmann, 2008; 44b
Rechenmacher, 2013; 1
2 (K34c)
3,1
1624
Heckmann, 2008; 34c
Martinkova , 2010; K34c
Janouskova, 2013; K34c 3
108
0,65
Neubauer, 2014; 3
Supplementary Table 1. Structures and respective affinities of the different small non-peptidic compounds for α5β1 and αvβ3 integrins.
References
Heckmann et al, ChemBioChem, 2008, 9(9):
Janouskova et al, Cancer Letters, 2013, 336:
Martinkova et al, Int. J. Cancer, 2010, 127:
Neubauer et al, J. Med. Chem,, 2014, 57(8):
Rechenmacher et al, Angew.Chem.Int.Ed., 2013, 52: