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Incorporating New Therapies in IBS-C

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Presentation on theme: "Incorporating New Therapies in IBS-C"— Presentation transcript:

1 Incorporating New Therapies in IBS-C

2 Patient Case

3 Is it Irritable Bowel Syndrome With Constipation?

4 What is IBS?

5 Pathophysiology of IBS

6 When Constipation Does Not Respond to First-line Treatment

7 IBS Diagnostic Testing

8 Cornerstones of Treatment for the Patient With IBS

9 Are Behavioral Therapies Useful in IBS?

10 Antispasmodics, Antidepressants, Laxatives

11 New and Emerging Treatments

12 Long-term Efficacy of Lubiprostone: Monthly Responder Rates

13 Effects of Guanylate Cyclase-C Receptor Activation

14 Linaclotide for IBS-C: Adequate Relief of IBS Symptoms for ≥ 13/26 Weeks

15 Prucalopride for Chronic Constipation Post-hoc Analysis of Phase III Data From Patients Who Had Failed Previous Laxative Therapies

16 Elobixibat: Mechanism of Action

17 Patient Case: Conclusion

18 Abbreviations

19 Abbreviations (cont)

20 References

21 References (cont)

22 References (cont)

23 References (cont)


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