1. Blood Diseases/Disorders
M. Rich, RN, BSN

2. Bell Work
What blood test gives numerous blood counts, calculations, and microscopic evaluations of blood cells?
What measures your sugar (glucose) level, electrolyte and fluid balance, kidney function, and liver function
What provides an average of your blood sugar control over the past 2 to 3 months?
What measures the cholesterol in your blood in the absence of food?

3. Bell Work Answers CBC – Complete Blood Count
CMP – Complete Metabolic Count
HgB A1 C
Fasting Lipid Panel

4. Standard
18) Outline the in-depth normal structure and function of blood and related components. Summarize appropriate medical text(s) in order to list signs and symptoms of common blood diseases and disorders associated with each. Define the following common laboratory procedures, both normal and abnormal, and provide the reasoning for why the test should be obtained:
a. Complete Blood Count
b. Complete Metabolic Panel
c. Fasting Lipid Panel
d. Hgb A1C

5. Objectives
Summarize appropriate medical text(s) in order to list signs and symptoms of common blood diseases and disorders associated with each

6. Diseases/Conditions Iron-Deficient Anemia (Meagan, Jaylie, Kelton)
Sickle Cell Anemia (Jon, Taha, Katlyn)
Leukemia, Lymphoma, Myeloma (Matt, Rebecca, Josie)
Leukocytosis (Lou, Hannah, Elsayed)
Leukopenia (Madison, Harley, Madi)
Thrombocytopenia (Caleb, Abby, Daegan)
Disseminated intravascular coagulation (DIC) (Anna, Kennedy)
Deep Vein Thrombosis (Chrissy, Sugey, Josie)
Pulmonary Embolism (Mary Mack, Allison)

7. Disease Research: Complete today, Present Tomorrow
Describe disease and it’s process
Who is susceptible? Or How do people get it?
What are the symptoms?
How is it diagnosed? ( what blood test?)
How is it treated?
Include one visual element
Create poster and be ready to present with group tomorrow in class

8. Bell Work 3-16-18 What is the medical term for bleeding?
What is the study of blood called?
What is the name of physician who studies blood disorders?
What is the White Blood Cell that indicates a chronic infection and travels in the blood stream?
What is the White Blood Cell that would release histamine due to an inflammatory response?

9. Anemia
Decrease in the number of RBC or hemoglobin in the circulating blood.
don't have enough healthy red blood cells to carry adequate oxygen to the body's tissues
Many types
Can you recall any types from Health Science?
Can you list any symptoms that might be seen in someone with anemia?

11. Iron- Deficiency Anemia
Most Common
is usually due to chronic blood loss caused by excessive menstruation, bleeding into or from the gut as a result of a peptic ulcer, gastritis, hemorrhoids. This condition is treated with iron supplementation
Iron deficiency occurs when the use of iron is more than its rate of absorption
common symptoms of chronic anemia include tiredness, weakness, shortness of breath and sometimes, a fast heartbeat.

12. Sickle Cell Anemia a group of inherited red blood cell disorders.
abnormal hemoglobin, called hemoglobin S or sickle hemoglobin, in their red blood cells.
It can form stiff rods within the red cell, changing it into a crescent, or sickle shape.
Sickle-shaped cells are not flexible and can stick to vessel walls, causing a blockage that slows or stops the flow of blood. When this happens, oxygen can’t reach nearby tissues.
Sickle cell disease is a life-long illness. The severity of the disease varies widely from person to person.
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13. Leukemia Cancer of the blood cells.
Marked increase in the number of abnormal or immature WBC in the bone marrow and circulating blood
Classified by the type of WBC affected
Types of Leukemia:
Myeloma: Cancer of the plasma cells - white blood cells that produce disease- and infection-fighting antibodies in your body. Prevent the normal production of antibodies, leaving your body's immune system weakened and susceptible to infection
Lymphoma: Cancer of the Lymphatic system. Abnormal lymphocytes, a type of white blood cell that fights infection, become lymphoma cells, which multiply and collect in your lymph nodes. Over time, these cancerous cells impair your immune system. ndex=3

14. Leukocytosis Abnormal increase in WBC
Most likely caused by a bacterial infection or dehydration

15. Leukopenia Abnormal decrease in the number of WBC
Causes: medications, failure of bone marrow, chemotherapy

16. Thrombocytopenia
Abnormal decrease in the number of circulating platelets
Sx: Bruising, frequent nosebleeds
Causes: failure of bone marrow, or increased platelet destruction by various factors

17. Diseases Associated With Coagulation Disorders
Disseminated intravasular coagulation (DIC)— serious disorder in which the proteins that control blood clotting become overactive.
Causes: cancer, septicemia, blood transfusion reactions, complications of pregnancy
Sx: blood clots, severe bleeding, death

18. Diseases Associated With Coagulation Disorders
Thrombophilia is an abnormality of blood coagulation that increases the risk of thrombosis (blood clots in blood vessels).[
The most common conditions associated with thrombophilia are deep vein thrombosis (DVT) and pulmonary embolism (PE)
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19. Diseases Associated With Coagulation Disorders
Hemophilia—hereditary disorder characterized by abnormal clotting
Sx: excessive bleeding
Tx: clotting factor transfusion