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Liver Cancer Checks in When Bile Acid Clocks Out

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Presentation on theme: "Liver Cancer Checks in When Bile Acid Clocks Out"— Presentation transcript:

1 Liver Cancer Checks in When Bile Acid Clocks Out
Ting Fu, Xuan Zhao, Ronald M. Evans  Cancer Cell  Volume 30, Issue 6, Pages (December 2016) DOI: /j.ccell Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Induction of HCC by Chronic Jet Lag Results from Global Gene Dysregulation Mediated through FXR and CAR Disruption of the peripheral clock by chronic jet lag leads to a sequential progression from NAFLD to NASH, cirrhosis, and ultimately HCC due to global metabolic dysfunction and gene dysregulation mediated through FXR and CAR. Cancer Cell  , DOI: ( /j.ccell ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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