1. Brainstorm: What is survival of the fittest?
Catalyst
Brainstorm: What is survival of the fittest?
How is this related to genetics?
I will use proper terms to describe DNA.

2. Today… DNA vocabulary What Darwin Never Knew
What Darwin Never Knew (38.18 or 31.30)
DNA vocabulary
What Darwin Never Knew

3. DNA - deoxyribonucleic acid, information storage, made up of nucleotides.
Chromosome - a molecule of DNA that passes from parent to offspring
Gene - a piece of a chromosome that codes for a specific trait
Allele – a type of gene
Think about genes and alleles like this…
We all have eye color – which color varies.

5. What would happen if DNA changed every time it was copied?
Catalyst
What would happen if DNA changed every time it was copied?
I will describe the parts and predict connections in DNA.

6. Today… What Darwin Never Knew (~10 minutes) DNA structure notes
DNA structure practice

7. (b) Franklin’s X-ray diffraction photograph of DNA
Fig. 16-6
Figure 16.6 Rosalind Franklin and her X-ray diffraction photo of DNA
(a) Rosalind Franklin
(b) Franklin’s X-ray diffraction photograph of DNA

8. Fig. 16-1
Figure 16.1 How was the structure of DNA determined?

9. Nitrogenous bases Phosphate Guanine (G)
Fig. 16-5
Sugar–phosphate backbone ′ end
Nitrogenous bases
Thymine (T)
Figure 16.5 The structure of a DNA strand
Adenine (A)
Cytosine (C)
DNA nucleotide
Phosphate
Sugar (deoxyribose) ′ end
Guanine (G)

10. 5′ end Hydrogen bond 3′ end 1 nm 3.4 nm 3′ end 0.34 nm 5′ end
Fig. 16-7
5′ end
Hydrogen bond
3′ end
1 nm
3.4 nm
Figure 16.7 The double helix
For the Cell Biology Video Stick Model of DNA (Deoxyribonucleic Acid), go to Animation and Video Files.
For the Cell Biology Video Surface Model of DNA (Deoxyribonucleic Acid), go to Animation and Video Files.
3′ end
0.34 nm
5′ end
(a) Key features of DNA structure
(b) Partial chemical structure
(c) Space-filling model

11. Purine + purine: too wide
Fig. 16-UN1
Purine + purine: too wide
Pyrimidine + pyrimidine: too narrow
Purine + pyrimidine: width consistent with X-ray data

12. Cytosine (C) Adenine (A) Thymine (T) Guanine (G) Fig. 16-8
Figure 16.8 Base pairing in DNA

13. (a) Key features of DNA structure (b) Partial chemical structure
Fig. 16-7a
5′ end
Hydrogen bond
3′ end
1 nm
3.4 nm
Figure 16.7 The double helix
3′ end
0.34 nm
5′ end
(a) Key features of DNA structure
(b) Partial chemical structure

14. Practice! Work through the review questions.
When you finish, use the nucleotides to build the completed strand.
Color code your nucleotides
Phosphate, sugar, adenine, thymine, cytosine, guanine

15. 03.03.16 Catalyst – Give two ways the structure of bases determines bonding.
Cytosine (C)
Adenine (A)
Thymine (T)
Guanine (G)

16. What Darwin Never Knew
Last ~15

17. Punnett Squares
Use parent genotype (combination of alleles) to predict off spring phenotype (physical appearance)
For example… If tall plants are dominant to short plants:
Give the percent of tall offspring resulting from a cross between two heterozygous tall plants.

18. Describing genotypes Heterozygous - Aa Homozygous dominant - AA
Homozygous recessive – aa

19. 03.08.16 Catalyst - Make three observations about the image.
Objective - I will model DNA replication.

20. Today. DNA replication animation Modeling DNA with k’nex.
DNA replication (realistic).
Amoeba sisters – animation intro
HHMI – realistic

21. Catalyst
In DNA replication, helicase unwinds the molecule. What happens next?
Today – I will review our DNA information so far.

22. DNA realistic animation
Review the unit so far
Quiz tomorrow!

23. 03.10.16 Catalyst What are Chargaff's rules? Why are the important?
I will demonstrate my DNA knowledge.

24. Packet review/study time
I will walk around and check off completed work
Review/clarifying questions
Quiz!

25. 03.11.16 Name a strategy you will use on the Science ACT.
Complete the reflection side.