1. Cytokine Review
7 November :43 PM

2. Anti-TNF antibody Used in rheumatoid arthritis
Adalimumab
TNF inhibitor
Anti-TNF antibody Used in rheumatoid arthritis

3. Inflammatory mediator Plasma, hypotension, pain
Bradykinin
Inflammatory mediator
Plasma, hypotension, pain

4. C3a, C5a Inflammatory mediators
Anaphylatoxins Low molecular weight complement cleavage products

5. Cromolyn sodium Mast cell stabilizer
Inhibits release of mast cell mediators Used prophylactically in asthma

6. Primary regulator of RBC synthesis
Erythropoietin (EPO)
Cytokine
Primary regulator of RBC synthesis

7. Etanercept TNF inhibitor
Tumor necrosis factor receptor + Fc portion of IgG Used in rheumatoid arthritis

8. Granulocyte-Colony Stimulating Factor (G-CSF)
Cytokine
Granulocyte synthesis stimulator

9. Granulocyte/Monocyte-Colony Stimulating Factor (GM-CSF)
Cytokine
WBC (granulocytes and monocyte) synthesis stimulator

10. Inflammatory mediator Stored in mast cells and basophils
Histamine
Inflammatory mediator
Stored in mast cells and basophils

11. Anti-TNF monoclonal antibody Treatment of IBD
Infliximab
TNF inhibitor
Anti-TNF monoclonal antibody Treatment of IBD

12. Antiviral for hepatitis Antineoplastic Cytokine
Interferon alpha
Antiviral for hepatitis Antineoplastic Cytokine
Anti-angiogenesis

13. Cytokine Antineoplastic
Interleukin 2
Cytokine Antineoplastic

14. Cytokine Antineoplastic (supporting agent)
Interleukin 11
Cytokine Antineoplastic (supporting agent)

15. Inflammatory mediator Plasma, hypotension, pain
Kallidin
Inflammatory mediator
Plasma, hypotension, pain

16. Leukotriene B4 (LTB4) Inflammatory mediator
Lipoxygenase product of arachidonate metabolism Chemotactic

17. Leukotrienes C4, D4, E4 (LTC4, LTD4, LTE4)
Inflammatory mediators
Cysteinyl leukotrienes Peptidyl leukotrienes SRS-A Lipoxygenase products of arachidonate metabolism

18. Leukotriene inhibitor LTR1 and LTD4 antagonist Asthma treatment
Montelukast
Leukotriene inhibitor
LTR1 and LTD4 antagonist Asthma treatment

19. Nedocromil Mast cell stabilizer
Inhibits release of mast cell mediators Used prophylactically in asthma

20. Platelet Activating Factor (PAF)
Inflammatory mediator
Lipid Hypotensive

21. Prostaglandin E2 (PGE2) Dinoprostone (Dinoprost)
Oxytocic prostaglandin Inflammatory mediator
Cyclooxygenase product of arachidonate metabolism Uterine stimulant Cervical ripener

22. Prostaglandin F2 (PGF2) Inflammatory mediator
Cyclooxygenase product of arachidonate metabolism

23. Inflammatory mediator
Prostaglandin I2 (PGI2)
Prostacyclin
Inflammatory mediator
Inhibits platelet aggregation Cyclooxygenase product of arachidonate metabolism

24. Platelet synthesis stimulator
Thrombopoietin
Cytokine
Platelet synthesis stimulator

25. Thromboxane A2 (TXA2) Autacoid
Promotes platelet aggregation Cyclooxygenase product of arachidonate metabolism

26. Tumor necrosis factor 
Cytokine Antineoplastic

27. Leukotriene inhibitor LTR1 and LTD4 antagonist Asthma treatment
Zafirlukast
Leukotriene inhibitor
LTR1 and LTD4 antagonist Asthma treatment

28. Leukotriene inhibitor 5-lipoxygenase inhibitor Used in asthma
Zileuton
Leukotriene inhibitor
5-lipoxygenase inhibitor Used in asthma