1. The Ever-Expanding Patient Pool for TAVR:

2. This program will include a discussion of off-label uses of devices that have FDA approval for use in patients with prohibitive or high surgical risk. The off-label use is with regard to use in patients with an intermediate risk for cardiothoracic surgery.

3. Aortic Stenosis

4. Recent Intermediate-Risk TAVR Trials

5. SURTAVI: Trial Design

6. SURTAVI: Baseline Characteristics

7. SURTAVI: Frailty, Disabilities, and Comorbidities

8. SURTAVI: All-Cause Mortality or Disabling Stroke

9. SURTAVI: All-Cause Mortality

10. Instantaneous Hazard of Mortality

11. SURTAVI: Disabling Stroke

12. SURTAVI: 30-Day Safety and Procedure-Related Complications

13. SURTAVI: Total Aortic Regurgitation

14. SURTAVI: Vascular Complications and Bleeding

15. SURTAVI: Pacemaker Implantation

16. SURTAVI: Key Takeaways

17. Conclusion

18. Abbreviations

19. Abbreviations (cont)