1. Hot Topics in Neonatology Neonatal Respiratory Symposium Nasal High Flow Therapy – Evidence Base for Preterm Infants Dr Louise Owen, MD

2. Hot Topics in Neonatology Neonatal Respiratory Symposium Nasal High Flow Therapy – Evidence Base for Preterm Infants I have no financial relationships to disclose Dr Louise Owen, MD

3. Emergence of Neonatal nHF…

4. CPAP Isn’t the Answer for Everyone…

5. Emergence of Neonatal nHF…

6. nHF Delivery Devices

7. Nasal-HF Pre-2010

8. nHF Use in NICUs…

9. nHF Use in Australia + NZ (ANZNN)

10. nHF Cochrane Review 2011

11. nHF Mechanisms of Action…

12. nHF Mechanisms of Action…

13. nHF Mechanisms of Action…

14. nHF Mechanisms of Action…

15. nHF Mechanisms of Action…

16. nHF Mechanisms of Action…

17. nHF Mechanisms of Action…

20. nHF Mechanisms of Action…

22. Pressure Increases with Flow

23. Pressure Increases with Flow

24. Pressure Increases with Flow

25. Effect on End Expiratory Lung Volume…

26. Prong: Nostril Ratio

27. Distending Pressure from nHF

28. Early nHF Trials…

29. Cochrane Review nHF

41. Post Extubation: Pneumothorax

42. Post Extubation: Nasal Trauma

43. Post-Extubation: Duration of Support

47. nHF as Primary Respiratory Support

48. nHF as Primary Respiratory Support

49. nHF as Primary Respiratory Support

50. nHF as Primary Respiratory Support

51. nHF as Primary Respiratory Support

52. nHF as Primary Respiratory Support

53. nHF as Primary Respiratory Support

54. nHF as Primary Respiratory Support

55. Lavizzari – Outcomes

56. Roberts (HIPSTER) – Outcomes

57. Primary Support: Treatment Failure – ‘16

58. Primary Support: Treatment Failure - Now

59. Primary Support: Treatment Failure - Now

60. Primary Support: Pneumothorax

61. Primary Support: Pneumothorax

62. Primary Support: Nasal Trauma

63. Primary nHF vs. NIPPV

64. nHF as Primary Support - Summary

65. nHF as Primary Support - Summary

66. nHF as Primary Support - Summary

67. nHF as Primary Support - Summary

68. Do Non-tertiary SCNs use nHF?