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Inherited Disorders of Bilirubin Transport and Conjugation: New Insights Into Molecular Mechanisms and Consequences Serge Erlinger, Irwin M. Arias, Daniel Dhumeaux Gastroenterology Volume 146, Issue 7, Pages (June 2014) DOI: /j.gastro Copyright © 2014 AGA Institute Terms and Conditions
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Figure 1 Schematic representation of the UGT1A1 locus and UGT1A1 protein. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2014 AGA Institute Terms and Conditions
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Figure 2 Schematic view of bilirubin transport by the hepatocyte. (Inset) Localization of UGT1A1 in the reticulum endoplasmic membrane and transport of uridine diphospho-glucuronic acid (UDPGA), bilirubin, and bilirubin glucuronide across the endoplasmic reticulum membrane. UCB, unconjugated bilirubin; Alb, albumin; BG, bilirubin glucuronide. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2014 AGA Institute Terms and Conditions
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Figure 3 Schematic view of the transporters involved in inherited disorders of bilirubin metabolism. UCB, unconjugated bilirubin; Alb, albumin; BG, bilirubin glucuronide. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2014 AGA Institute Terms and Conditions
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