1. Chapter 88: Sclerosing Bone Disorders
Michael P. Whyte

2. Table 1. Disorders That Cause High Bone Mass
From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition.
Table 1. Disorders That Cause High Bone Mass
© 2008 American Society for Bone and Mineral Research

3. From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition.
Figure 1
Figure 1 Osteopetrosis. Anteroposterior radiograph of the distal femur of a 10-yr-old boy shows a widened metadiaphysis with characteristic alternating dense and lucent bands. (Reprinted with permission from Whyte MP, Murphy WA 1990 Osteopetrosis and other sclerosing bone disorders. In: Avioli LV, Krane SM (eds.) Metabolic Bone Disease, 2nd ed. Saunders, Philadelphia, PA, USA, p. 618.)
Figure 1 Osteopetrosis. Anteroposterior radiograph of the distal femur of a 10-yr-old boy shows a widened metadiaphysis with characteristic alternating dense and lucent bands. (Reprinted with permission from Whyte MP, Murphy WA 1990 Osteopetrosis and other sclerosing bone disorders. In: Avioli LV, Krane SM (eds.) Metabolic Bone Disease, 2nd ed. Saunders, Philadelphia, PA, USA, p. 618.)

4. From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition.
Figure 2
Figure 2 Osteopetrosis. A characteristic area of lightly stained calcified primary spongiosa (arrows) is found within darkly stained mineralized bone.
Figure 2 Osteopetrosis. A characteristic area of lightly stained calcified primary spongiosa (arrows) is found within darkly stained mineralized bone.
© 2008 American Society for Bone and Mineral Research

5. From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition.
Figure 3
Figure 3 Progressive diaphyseal dysplasia (Camurati-Engelmann disease). The distal radius of this 20-yr-old woman has characteristic patchy thickening (arrow) of the periosteal and endosteal surfaces of the diaphysis.
Figure 3 Progressive diaphyseal dysplasia (Camurati-Engelmann disease). The distal radius of this 20-yr-old woman has characteristic patchy thickening (arrow) of the periosteal and endosteal surfaces of the diaphysis.
© 2008 American Society for Bone and Mineral Research

6. From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition.
Figure 4
Figure 4 Osteopoikilosis. The characteristic feature is the spotted appearance shown here in the pelvis and metaepiphyseal regions of the femora. [Reproduced with permission from Whyte MP 1995 Rare disorders of skeletal formation and homeostasis. In: Becker KN (ed.) Principles and Practice of Endocrinology and Metabolism, 2nd ed. Lippincott-Raven Publishers, Philadelphia, PA, USA, p. 598.)
Figure 4 Osteopoikilosis. The characteristic feature is the spotted appearance shown here in the pelvis and metaepiphyseal regions of the femora. [Reproduced with permission from Whyte MP 1995 Rare disorders of skeletal formation and homeostasis. In: Becker KN (ed.) Principles and Practice of Endocrinology and Metabolism, 2nd ed. Lippincott-Raven Publishers, Philadelphia, PA, USA, p. 598.)

7. From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition.
Figure 5
Figure 5 Melorheostosis. Characteristic patchy osteosclerosis is most apparent in the radius and second metacarpal of this 8-yr-old girl.
Figure 5 Melorheostosis. Characteristic patchy osteosclerosis is most apparent in the radius and second metacarpal of this 8-yr-old girl.
© 2008 American Society for Bone and Mineral Research