1. Global AMR R&D Hub
Brussels, 26. February 2018

2. International consensus: AMR is a major threat
G20 Leaders’ Communiqué 2017: a “new international R&D Collaboration Hub” is needed
G20 Health Working Group agreed:
Comprehensive strategy is needed to fight AMR
Increased funding and incentives for R&D are necessary
A global One Health approach is mandatory
International collaboration on R&D has to be fostered
Oct 2017: Global AMR R&D Hub, start of the interim phase
22 May 2018: Official launch at the WHA, Geneva, Switzerland

3. Vision
The vision of the Global AMR R&D Hub is to be a key actor having an integrating role in global R&D for AMR, by
bringing together governments and upstream funders from around the world,
setting the focus on addressing global R&D priorities while respecting domestic and organizational priorities,
promoting high-level coordination and alignment of existing public and private funding and activities, and
leveraging much needed further monetary and other investments for AMR R&D.
Angepasst aus Work plan

4. Objectives to inform high-level decision makers,
to facilitate the efficient allocation of resources,
to promote increased investments,
to foster international research collaboration at a high level,
to support the filling of product pipelines with priority candidates,
to keep attention on AMR at high political levels.

5. Scope
One Health Approach, with initial focus on bacterial infections in humans
Global political level, no technical or scientific decision-making
Not a funding body, but support evidence-based political decision-making on allocation of resources for AMR R&D
Maximize the impact of existing and new initiatives in AMR R&D, including push and pull incentives
Build on existing efforts, therefore preventing duplication
Alignment with WHO, FAO and OIE priorities

6. Participation Members:
open to countries and upstream funders committing to take visible, significant and measurable action
currently 18 members
Observers:
relevant intergovernmental organisations
currently 2 observers: WHO, OECD
Other participation:
Strong interaction with relevant stakeholders, e.g. Advisory Groups, exchange of information

7. Status
Interim Phase approaching its end: finalisation of Terms of References, provisional work plan
Provisional work plan :
Develop a close to real-time Dynamic Dashboard
Define main operational activities and procedures
Secretariat is being set up, job interviews for the lead of the secretariat
Official inauguration on 22 May 2018 as a side-event to the World Health Assembly (WHA), Geneva, Switzerland

8. The Hub in the landscape of AMR initiatives
The Global AMR R&D Hub will:
focus on guiding ‘macro’ level decision-making by governments and upstream funders, rather than more technical and scientific decision-making,
serve an integrating function, bringing together information from different countries and initiatives around the world,
The Global AMR R&D Hub will rely on information and data from
Member states and organisations,
Intergovernmental organisations,
established implementors e.g. initiatives with a scientific focus, pipeline coordinators and other relevant stakeholders.
Information will be fed back to stakeholders

9. Hub collects & processes information
Members
AUS
BMGF
NOR
RUS
ESP
CAN EU
FRA
ITA
NLD
JPN WT
DEU
USA
GBR
TUR
BRA
CHN
Other
stakeholders
GARDP
Implementors
JPIAMR …
CARB-X
Global AMR R&D Hub
Multilaterals
OIE
FAO
WHO
OECD
TATFAR
IACG
Constant flow of information on current initiatives, funding flows, implementors and R&D activities, will be analysed and show gaps [SIEHE GRAFIK] and opportunities for the engagement of the members.

10. Hub feeds back to members and stakeholders
AUS
BMGF
NOR
RUS
ESP
CAN EU
FRA
ITA
NLD
JPN WT
DEU
USA
GBR
TUR
BRA
CHN
Other
stakeholders
GARDP
Implementors
JPIAMR …
CARB-X
Global AMR R&D Hub
Multilaterals
OIE
FAO
WHO
OECD
TATFAR
IACG
Information and advice for policy makers for their decision making on strategic investments
Identifiy gaps

11. Members take action Members GARDP CARB-X JPIAMR … task
AUS
BMGF
NOR
RUS
ESP
CAN EU
FRA
ITA
NLD
JPN WT
DEU
USA
GBR
TUR
BRA
CHN
Other
stakeholders
GARDP
Implementors
JPIAMR …
CARB-X
task
Support/
Financing
Exchange, cooperation
Global AMR R&D Hub
Multilaterals
OIE
FAO
WHO
OECD
TATFAR
IACG

12. At a glance: The Global AMR R&D Hub
The Board:
currently 18 members: Countries and upstream funders
currently 2 observers: Relevant intergovernmental organisations
Major objectives:
to inform and collaborate on a global, political level,
to identify and prioritise R&D gaps and facilitate efficient allocation of resources,
to increase investments into AMR R&D and keep attention, visibility and awareness at all levels.
Possible first deliverable:
Dynamic Dashboard with up to date information on funding flows and activities
Secretariat:
first 3 years in Berlin, Germany; one lead, 3-4 staff

13. Open for questions and discussion
Thank you!
Open for questions and discussion
Dr. Joachim Klein,
Division Global Health Research,
German Federal Ministry of Education and Research,