1. Virus: Microlife Infectious Diseases
Objective: you will be able to understand and explain how viruses attack and effect human cells

2. Intro: Infectious Disease Terms
Disease which travels easily from one organism to another: Can also travel between species as well
Pandemic – fast spreading international outbreak
Epidemic- wide spread out break of disease at a specific location
Asian Bird Flu 2007

3. Pathogen Pathogen- Any organism that causes diseases
Carrier- any human giving a disease to another human
Vector- any NON-HUMAN source of a disease being passed on to a human
Diseases are primarily responsible for damaging individual cells, which causes us “sickness” symptoms” as cells break down
Ex: sore throat

4. 4 Forms of Pathogens
Virus
Bacteria
Fungi
Protists
Bacteria

5. What are Viruses?

6. Viruses
Non- Living: Do not require any energy to survive; No food/gas needs
Extremely Small Organism made up of DNA or RNA and a Protein Coat : CAPSID
Only capable of reproducing itself by “hi-jacking” another cell
HIV Virus

7. 3 Main forms of Viruses (Norovirus) /Polyhedral Bacteriophage
(Filovirus)/ Rod Shaped )

8. All viruses have two types of infection cycles
Lytic Cycle (Active) show signs of sickness immediately
Lysogenic Cycle (Non Active) no illness creates “provirus cells” within body then becomes active

9. Lysogenic Cycle Shows no disease symptoms, may carry virus for years
FACT: HIV can stay like this for over 10 YEARS!!
1. Virus attaches to host
2. Viral DNA integrates or combines with cells DNA; becomes a “provirus” cell
3. As cell splits and divides virus replicates with cell creating more “provirus” cells
4. Some trigger activates virus: become ill

10. Lytic Cycle Show disease symptoms Virus actively attacking cells
1. Virus attaches to host cell
2. Virus enters host cell
3. Virus destroys host cell’s DNA, replaces DNA with its own VIRAL DNA
4. “Hijacked” cell creates more Viral DNA and protein coating
5. Lysis-host cell ruptures and releases hundreds of new virus to attack more cells

11. Common Viruses Chicken pox Herpes HIV Ebola Epstein Bar (mono) Mumps
Warts
Influenza
Hepatitis
Common Cold

12. How we fight back: Vaccines