1. The Industrial Strategy Challenge Fund & the Focus on Life Sciences
Ian Campbell, Director Health & Life Sciences, Innovate UK

2. Delivering Better Outcomes
Business
People
Place
Infrastructure
Accelerating UK economic growth through funding and connecting business-led innovation
Innovation:
Delivering Better Outcomes
KNOWLEDGE
ECONOMY
SOCIETY

3. Industrial Strategy Challenge Fund
£31bn National Productivity Investment Fund (NPIF) increased in Autumn Budget 2017
Industrial Strategy Challenge Fund
(£TBC over four years to FY21/22)
£7bn R&D Funding
(over four years to FY21/22)
Innovation, Applied Science & Research
(£TBC over four years to FY21/22)

4. Creating an economy that boosts productivity and earning power throughout the UK

5. Industrial Strategy Grand Challenges
AI and Data Economy
Ageing Society
Clean Growth
Future of Mobility

6. How the ISCF challenges fit with the
Industrial Strategy Grand Challenges
Clean growth
Energy revolution
Transforming construction
Transforming
food production
Ageing Society
Medicines manufacturing
Data to early diagnosis and precision medicine
Healthy ageing
Future of mobility
Faraday battery challenge
Extreme robotics
National space test facility
Artificial intelligence and data economy
Audience of the future / Next generation services (pioneer) / Quantum technology (pioneer)

7. Wave 1 – Medicines Manufacturing
£146m to develop first-of-a-kind technologies for the manufacture of tomorrow’s medicines, accelerating patient access to new drugs and treatments:
pharmaceuticals
vaccines
advanced therapies +
Digital Health Technology Catalyst
£35m to develop digital health or digitally-enabled medical technologies to:
improve patient outcomes
transform healthcare delivery
enable more efficient delivery of healthcare

8. The challenge has 2 investment streams: innovation and scale-up
Stage 1: Collaborative Research and Development
Competitive funding calls to support development and innovation to translate scientific, clinical, digital, engineering or manufacturing research into a proof of concept demonstration.
Industry-led activity between academic, technology providers, and supply chain companies
Demonstrating the feasibility of new technologies and new medicines
Stage 1: Innovation £90m
Stage 2: Scale-up £91m

9. The challenge has 2 investment streams: innovation and scale-up
Stage 1: Collaborative Research and Development
Three competitive funding calls have been run and initial funding awarded:
Digital Health Technology Catalyst (total fund £35m)*
Medicines Manufacturing CR&D (total fund £25m)*
Advanced Therapies Treatment Centres (total fund £30m)
Stage 1: Innovation £90m
Stage 2: Scale-up £91m
* Round 2 calls for DHTC (£8m) & Medicines Manufacturing CR&D (£10m) open Feb and March 2018

10. The challenge has 2 investment streams: innovation and scale-up
Stage 2: Capital investment in UK medicines manufacturing infrastructure
Competitive funding calls for capital investment
Medicines Manufacturing Innovation Centre
Viral Vector production for cell and gene therapies
Vaccines Development & Manufacturing Centre
Stage 1: Innovation £90m
Stage 2: Scale-up £91m
In addition to these funding competitions £12m from the ISCF has been committed for Phase 2 of the Cell & Gene Therapy Manufacturing Centre

11. The challenge has 2 investment streams: innovation and scale-up
Stage 2: Capital investment in UK medicines manufacturing infrastructure
Support growth of UK medicines manufacturing capacity and capability to produce tomorrow’s medicines
Cell and gene therapies
Vaccines
Pharmaceuticals
Stage 1: Innovation £90m
Stage 2: Scale-up £91m

12. Awarded Funding Announced
ISCF Medicines Manufacturing
Committed
Digital Health Technology Catalyst
£12,882,157
Medicines Manufacturing CR&D
£14,517,574
Viral vector production for cell and gene therapies
£5,574,781
Phase 2 Cell & Gene Therapy Manufacturing Centre
£12,000,000
Establishing UK treatment centres for advanced therapies
£21,091,569
99 projects awarded funding in the ISCF Medicines Manufacturing Challenge

13. Wave 1 – Medicines Manufacturing
ISCF Competitions 2018
Fund
Status
Digital Health Technology Catalyst round 2
£8m
Opens 15/02/18
Medicines manufacturing round 2: challenge fund
£10m
Opens 12/03/18

14. Data to early diagnosis and precision medicine –
The challenge is to combine the wealth of data created by UK researchers with real world evidence from our health service. That will allow industry to create new products and services that will diagnose diseases earlier and help clinicians choose the best treatment for individual patients. This will save lives and set the UK at the forefront of a growing global market in diagnostics worth $217bn in 2016.

15. Healthy Ageing
The challenge is to develop new products and services that offer choice, meet their aspirations and through better, more effective care, support an independent lifestyle as they age. By working together, the government and industry can address the challenges of ageing whilst capturing a growing global market.

16. Transforming food production: from farm to fork
The challenge is that our food needs to be much more efficient and sustainable. By using precision technologies we can make that a reality: transform food production while reducing emissions, pollution, waste, and soil erosion. By putting the UK at the forefront of this global revolution in farming, we will delivering benefits to farmers, the environment and consumers while driving growth, jobs and exports.

17. ISCF Wave 2 Challenges
10 challenges being progressed, 2 in Health and Life Science:
Data to Early Diagnostics and Preventative Medicine - £210m
Genomics – WGS of 500,000 UK Biobank Samples & 25,000 (x2) cancer patients
Digital innovation Hubs – Industry access to clinical data – an NHS, HDR-UK & industry collaboration
Digital Pathology, Digital Radiology & AI/Informatics – an NHS, industry, SME collaboration
Healthy Ageing - £90m
Three place-based development and demonstrators (PBDs).
Collaborative Research & Development (CR&D) for the development of new products and services.
Behavioural research to support business needs
Industrial Strategy Challenge Fund
A £75m R&D competition to identify 3 PBDs sought from existing centres of excellence with scientific depth of experience and facilities. PBDs would provide a focal point for user and customer engagement, open access for microbusinesses and SMEs and for new partners to come together.
Providing financial support to microbusinesses, SMEs and academics to develop new products and services for older adults through £18m of private sector matched funding. It would build on digital healthcare and other funding focused on older adults.
by informing product development, patterns of adoption and use and thereby reducing the risks in the environment within which businesses operate. Matched in kind a £5m contribution from partners

18. ISCF Wave 3
“We will run a third wave of Industrial Strategy Challenge Fund programmes, with UK Research and Innovation launching an expression of interest for potential challenges”

19. Health & Life Science Competitions

20. Open sector competition Round 4 £19m
Open Competitions
Amount
Deadline
Open sector competition Round 4
£19m
28th Feb ’18
Support for SME’s to evaluate the Innovative Medical Technologies (OLS)
£1m
21st March ‘18
Asthma UK/Innovate UK
£750k /£500k (IUK)
27th March ’18
Health & Life Sciences/ Emerging and Enabling Technologies Sector Competition
28th March ’18
Digital Health Technology Catalyst 2018 R2
£8m
18th April ‘18
NHS Test Beds Wave 2
£5.5m
April ‘18

21. Planned Competitions Planned Opening UK-China AMR
TBC (Feb’18 - April ’18)
ISCF Medicine Manufacturing R2
12th March ’18
Biomedical Catalyst R1
26th March ’18