1. M/Z Cal Issues at high mass loadings
Brett Palm
Jimenez Group
CU-Boulder
My problem: At very high mass loadings (~thousand ug/m3), organic peak interference at various masses (eg Ar, W) causes problems with the m/z cal

2. Example of Argon m/z 40 successive V-mode runs, high loadings start in r2349:

3. Possible fixes (in no particular order):
Don’t use that mass, manually use another
May need separate ToDo waves for high and low mass loadings
Peak search factor
Changes the window where it searches for the peak
Change the value of Delta for that mass
Adjusts the number of points it tries to fit
Filter Bad Parameters in Step 4
Find a threshold that you think defines the bad fits
Choose replacement method
Interpolate
Repeat last good fit
Use logging (from DAQ, probably not recommended for most apps)
Make sure “# runs where fit = nan” is zero before you hit ‘End’