1. Lysosomal Acid Lipase Deficiency: Paving the Path for an Early Diagnosis

3. Program Goals

4. LAL-D

5. Prevalence of LAL-D

7. LAL-D in Adults and Children

8. Histology

9. Histology (cont)

10. Histology: Differential Diagnosis

11. Confirm the Diagnosis of LAL-D Using an LAL Enzyme Activity Assay

12. LAL Blood Tests: Dried Blood, Spot Enzyme Assay

13. Differential Diagnosis

14. Liver Pathology: Mimics

15. Making the Final Diagnosis

16. Hepatic Function Is Progressively Compromised in Patients With LAL-D[a]

17. LAL-D Is Characterized by Dyslipidemia

18. LAL-D Is Multisystemic

19. Wolman Disease*

20. Some Patients Do Not Fit the Classic Lipid Profile

21. Management and Treatment of LAL-D

22. ARISE

23. ARISE: Primary Outcome

24. ARISE: Secondary Outcomes

25. LAL-D: Summary

26. Abbreviations