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The complex world of kidney microRNAs

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1 The complex world of kidney microRNAs
Balakuntalam S. Kasinath, Denis Feliers  Kidney International  Volume 80, Issue 4, Pages (August 2011) DOI: /ki Copyright © 2011 International Society of Nephrology Terms and Conditions

2 Figure 1 A schematic showing the generation and actions of miRNA. Ago, Argonaute; DGCR8, DiGeorge syndrome critical region 8; eIF4E, eukaryotic initiation factor 4E; GW182, glycine-tryptophan protein-182; nt, nucleotides; RISC, miRNA-induced silencing complex; TARBP, transactivation-responsive RNA-binding protein. Kidney International  , DOI: ( /ki ) Copyright © 2011 International Society of Nephrology Terms and Conditions

3 Figure 2 Role of miRNA in diabetic nephropathy. miR, miRNA; PTEC, proximal tubule epithelial cells; T1D, type 1 diabetes; T2D, type 2 diabetes; TGF-β1, transforming growth factor-β1. Arrows indicate stimulation; bars indicate inhibition. Kidney International  , DOI: ( /ki ) Copyright © 2011 International Society of Nephrology Terms and Conditions


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